Evidence map›Paper›PMID 30833778›Full record

ArticleNature chemical biology2019

Potassium channel selectivity filter dynamics revealed by single-molecule FRET.

Shizhen Wang, Sun-Joo Lee, Grigory Maksaev, Xin Fang, Chong Zuo, Colin G Nichols

Abstract read
In one paragraph

Article in Nature chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Cholesterol inhibits human voltage-gated proton channel hHv1.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Conformational changes upon gating of KirBac1.1 into an open-activated state revealed by solid-state NMR and functional assays.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Shizhen WangCenter for Investigation of Membrane Excitability Diseases, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA. wangshizhen@umkc.edu.ORCID http://orcid.org/0000-0003-1065-4756
Sun-Joo LeeCenter for Investigation of Membrane Excitability Diseases, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-6302-7986
Grigory MaksaevCenter for Investigation of Membrane Excitability Diseases, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0001-6242-1634
Xin FangCenter for Investigation of Membrane Excitability Diseases, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.
Chong ZuoCenter for Investigation of Membrane Excitability Diseases, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0001-6117-6438
Colin G NicholsCenter for Investigation of Membrane Excitability Diseases, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA. cnichols@wustl.edu.ORCID http://orcid.org/0000-0002-4929-2134

Funding

Role of vascular KATP channels in Alzheimer’s neurodegeneration and dementiaR35HL140024 · NHLBI · WASHINGTON UNIVERSITY · PI NICHOLS, COLIN G · 2018 to 2023
$5.9M
NHLBI NIH HHS R35 HL140024
6 · The paper itself

Abstract

Potassium (K) channels exhibit exquisite selectivity for conduction of K

Indexed as

AnimalsBinding SitesCell Membrane PermeabilityCrystallography, X-RayFluorescence Resonance Energy TransferHumansIon Channel GatingModels, MolecularPotassiumPotassium ChannelsProtein ConformationSingle Molecule ImagingSodiumStructure-Activity RelationshipPotassiumPotassium ChannelsSodium

Identifiers

PMID30833778
PMCPMC6430689

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.