Evidence map›Paper›PMID 30833706›Full record

ReviewNature reviews. Neuroscience2019

Novel electrode technologies for neural recordings.

Guosong Hong, Charles M Lieber

Erratum issuedAbstract readReview
In one paragraph

Review in Nature reviews. Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 268 papers.

0numbers the graph read from it
0cells of the map it votes in
268citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

268 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Fluorescence-lifetime optical electrophysiology in contracting cardiomyocytes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  11. Tissue-bioelectronics interfaces.Chemical Society reviews · 2026
    Review
  12. Article
  13. Fabrication of High-Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  14. Review
  15. Article
  16. Full-Stack Architectures for Intelligent Brain-Computer Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  17. Review
  18. Review
  19. Hands-free control of an assistive robotic arm for high-level paralysis.Journal of neuroengineering and rehabilitation · 2026
    Article
  20. An exceptionally conductive hydrogel for all-organic, ultraflexible, and chronic neural interfaces.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article

208 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Guosong HongDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
Charles M LieberDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA. cml@cmliris.harvard.edu.ORCID http://orcid.org/0000-0002-6660-2456

Funding

Syringe-Injectable Mesh Electronics for Seamless Integration with the Central Nervous SystemDP1EB025835 · NIBIB · HARVARD UNIVERSITY · PI LIEBER, CHARLES M · 2017 to 2019
$3.5M
Brain Aging Studies with Single-Neuron Resolution Using Syringe-Injectable ElectronicsR00AG056636 · NIA · STANFORD UNIVERSITY · PI HONG, GUOSONG · 2018 to 2020
$745k
NIA NIH HHS R00 AG056636NIBIB NIH HHS DP1 EB025835
6 · The paper itself

Abstract

Neural recording electrode technologies have contributed considerably to neuroscience by enabling the extracellular detection of low-frequency local field potential oscillations and high-frequency action potentials of single units. Nevertheless, several long-standing limitations exist, including low multiplexity, deleterious chronic immune responses and long-term recording instability. Driven by initiatives encouraging the generation of novel neurotechnologies and the maturation of technologies to fabricate high-density electronics, novel electrode technologies are emerging. Here, we provide an overview of recently developed neural recording electrode technologies with high spatial integration, long-term stability and multiple functionalities. We describe how these emergent neurotechnologies can approach the ultimate goal of illuminating chronic brain activity with minimal disruption of the neural environment, thereby providing unprecedented opportunities for neuroscience research in the future.

Indexed as

Action PotentialsAnimalsBrainElectrodesElectrodes, ImplantedHumansNeurons

Identifiers

PMID30833706
PMCPMC6531316

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.