ArticleScientific reports2019
The homotopic connectivity of the functional brain: a meta-analytic approach.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Sex differences in brain homotopic co-activations: a meta-analytic study.Brain structure & function · 2022Pooled it
- Tasks activating the default mode network map multiple functional systems.Brain structure & function · 2022Pooled it
- Hubs of long-distance co-alteration characterize brain pathology.Human brain mapping · 2020Pooled it
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- Changes in Cerebral Glucose Metabolism at Rest Following Hemicontusive Cervical Spinal Cord Injury in Mice: A Whole-Brain Autoradiographic Study.The European journal of neuroscience · 2026Article
- Aberrant Functional Lateralization and Interhemispheric Synergy in High Myopia: Insights From Neurotransmitter Distribution Signatures and Machine Learning Classification.Investigative ophthalmology & visual science · 2026Article
- Supplementary Motor Area During Motor Actions in Athletes With Neurological Disorders: Observational Study of Cases and Controls.Brain and behavior · 2026Observational
- Efficacy of 5-Hz Transcranial Magnetic Stimulation Over the Left Dorsolateral Prefrontal Cortex in Improving Cognitive Function During the Recovery Phase of Stroke.Brain and behavior · 2026Article
- Disrupted resting-state interhemispheric functional connectivity in patients with first-episode moyamoya disease.Scientific reports · 2025Article
- Multimodal integration of homotopic connectivity and transcriptomic signatures in major depressive disorder with sleep disorder comorbidity.BMC psychiatry · 2025Article
- Zero-phase-delay synchrony between interacting neural populations: implications for functional connectivity-derived biomarkers.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Structural and functional connectivity in relation to executive functions in antipsychotic-naïve patients with first episode schizophrenia and levels of glutamatergic metabolites.Schizophrenia (Heidelberg, Germany) · 2024Article
- Impaired interhemispheric synchrony and effective connectivity in right temporal lobe epilepsy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Long-range inhibitory neurons mediate cortical neurovascular coupling.Cell reports · 2024Article
- Activation Likelihood Estimation Neuroimaging Meta-Analysis: a Powerful Tool for Emotion Research.Psychology research and behavior management · 2024Review
- Alternations of interhemispheric functional connectivity in patients with acute acquired concomitant esotropia: a resting state fMRI study using voxel-mirrored homotopic connectivity.Frontiers in neuroscience · 2024Article
- When Age Tips the Balance: a Dual Mechanism Affecting Hemispheric Specialization for Language.bioRxiv : the preprint server for biology · 2023Article
- Language network lateralization is reflected throughout the macroscale functional organization of cortex.Nature communications · 2023Article
- The relevance of heterotopic callosal fibers to interhemispheric connectivity of the mammalian brain.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Spectrotemporal content of human auditory working memory represented in functional connectivity patterns.Communications biology · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Homotopic connectivity (HC) is the connectivity between mirror areas of the brain hemispheres. It can exhibit a marked and functionally relevant spatial variability, and can be perturbed by several pathological conditions. The voxel-mirrored homotopic connectivity (VMHC) is a technique devised to enquire this pattern of brain organization, based on resting state functional connectivity. Since functional connectivity can be revealed also in a meta-analytical fashion using co-activations, here we propose to calculate the meta-analytic homotopic connectivity (MHC) as the meta-analytic counterpart of the VMHC. The comparison between the two techniques reveals their general similarity, but also highlights regional differences associated with how HC varies from task to rest. Two main differences were found from rest to task: (i) regions known to be characterized by global hubness are more similar than regions displaying local hubness; and (ii) medial areas are characterized by a higher degree of homotopic connectivity, while lateral areas appear to decrease their degree of homotopic connectivity during task performance. These findings show that MHC can be an insightful tool to study how the hemispheres functionally interact during task and rest conditions.
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Registered trials
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