ArticleScientific reports2019
New molecular insights on the response of the green alga Tetraselmis suecica to nitrogen starvation.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 64 citations in OpenAlex.
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- Effects of nitrate limitation on the metabolome ofCurrent research in microbial sciences · 2025Article
- Immunomodulatory properties of polysaccharide extract samples from Cyanobacterium sp. Rippka B-1200.Scientific reports · 2024Article
- Comparative Transcriptomics to Identify RNA Writers and Erasers in Microalgae.International journal of molecular sciences · 2024Article
- Cell size, density, and nutrient dependency of unicellular algal gravitational sinking velocities.Science advances · 2024Article
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- Remediation Capacity of Different Microalgae in Effluents Derived from the Cigarette Butt Cleaning Process.Plants (Basel, Switzerland) · 2022Article
- Extracting protein from microalgae (MethodsX · 2022Article
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- Promising Activities of Marine Natural Products against Hematopoietic Malignancies.Biomedicines · 2021Review
- Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds.International journal of molecular sciences · 2021Review
- Evaluation of antioxidant and anticancer activity of crude extract and different fractions of Chlorella vulgaris axenic culture grown under various concentrations of copper ions.BMC complementary medicine and therapies · 2021Article
- Selection and validation of reference genes for quantitative real-time PCR in the green microalgae Tetraselmis chui.PloS one · 2021Article
- Physiological and Molecular Responses to Main Environmental Stressors of Microalgae and Bacteria in Polar Marine Environments.Microorganisms · 2020Review
- De novo Transcriptome of the Non-saxitoxin ProducingMarine drugs · 2020Article
- In Silico Identification of Type III PKS Chalcone and Stilbene Synthase Homologs in Marine Photosynthetic Organisms.Biology · 2020Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microalgae are currently considered one of the most promising resources for biofuel production, aquaculture feedstock and new pharmaceuticals. Among them, green algae of the genus Tetraselmis are extensively studied for their lipid accumulation in nutrient-starvation conditions. In this paper, we present the full-transcriptome of Tetraselmis suecica and differential expression analysis between nitrogen-starved and -repleted conditions (at stationary phase) focusing not only on lipid metabolism but giving new insights on nutrient starvation responses. Transcripts involved in signal transduction pathways, stress and antioxidant responses and solute transport were strongly up-regulated when T. suecica was cultured under nitrogen starvation. On the contrary, transcripts involved in amino acid synthesis, degradation of sugars, secondary metabolite synthesis, as well as photosynthetic activity were down-regulated under the same conditions. Among differentially expressed transcripts, a polyketide synthase and three lipoxygenases (involved in the synthesis of secondary metabolites with antipredator, anticancer and anti-infective activities) were identified, suggesting the potential synthesis of bioactive compounds by this microalga. In addition, the transcript for a putative nitrilase, enzyme used in nitrile bioremediation, is here reported for the first time for T. suecica. These findings give new insights on T. suecica responses to nutrient starvation and on possible biotechnological applications for green algae.
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