ArticleNature communications2019
A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Altered blood-based biomarkers in carpal tunnel syndrome. A systematic review and meta-analysis.Musculoskeletal science & practice · 2026Pooled it
- [The EAN-NeuPSIG guideline on the diagnosis of neuropathic pain-a summary].Schmerz (Berlin, Germany) · 2026Guideline
- Shared genetic architecture of hernias: A genome-wide association study with multivariable meta-analysis of multiple hernia phenotypes.PloS one · 2022Pooled it
- Examining the role of insulin-like growth factor 1 in the pathophysiology of carpal tunnel syndrome: a Mendelian randomization study.International journal of epidemiology · 2026Article
- Article
- Genetic underpinnings and causal effects of brain structure and function on chronic pain intensity.Nature communications · 2025Article
- Body mass index and the risk of ulnar nerve entrapment in individuals without diabetes-a longitudinal cohort study from Sweden.International journal of obesity (2005) · 2025Article
- Occupational biomechanical risk factors for carpal tunnel syndrome surgery: a prospective cohort study on 203 866 Swedish male construction workers followed for 19 years.Occupational and environmental medicine · 2025Article
- Computer Use and Compressive Neuropathies of the Upper Limbs: A Hidden Risk?Journal of clinical medicine · 2025Review
- Causal relationship between rheumatoid arthritis and carpal tunnel syndrome: a bidirectional two-sample Mendelian randomization study.Journal of orthopaedic surgery and research · 2024Article
- Impact of Exposure to Hand-Held Vibrating Tools on Patient-Reported Outcome Measures after Open Carpal Tunnel Release: A Retrospective Cohort Study with Matched Controls.Journal of clinical medicine · 2024Article
- Bioinformatics Analysis of Differentially Expressed Genes in Carpal Tunnel Syndrome Using RNA Sequencing.Iranian journal of public health · 2024Article
- Carpal tunnel syndrome.Nature reviews. Disease primers · 2024Review
- Relationship of obesity indices with clinical severity and nerve conduction studies in females presenting with median nerve compression neuropathy at the wrist.Journal of family medicine and primary care · 2024Article
- Genetic causal association between frozen shoulder and carpal tunnel syndrome: a two-sample mendelian randomization.BMC musculoskeletal disorders · 2024Article
- Screening Plasma Proteins for the Putative Drug Targets for Carpal Tunnel Syndrome.Cellular and molecular neurobiology · 2023Article
- Big data, big consortia, and pain: UK Biobank, PAINSTORM, and DOLORisk.Pain reports · 2023Article
- A comparative study on efficacy of modified endoscopic minimally invasive treatment and traditional open surgery for primary carpal tunnel syndrome.Journal of orthopaedic surgery and research · 2023Article
- Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review.Cellular and molecular neurobiology · 2023Review
- Dupuytren's disease is a work-related disorder: results of a population-based cohort study.Occupational and environmental medicine · 2023Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Carpal tunnel syndrome (CTS) is a common and disabling condition of the hand caused by entrapment of the median nerve at the level of the wrist. It is the commonest entrapment neuropathy, with estimates of prevalence ranging between 5-10%. Here, we undertake a genome-wide association study (GWAS) of an entrapment neuropathy, using 12,312 CTS cases and 389,344 controls identified in UK Biobank. We discover 16 susceptibility loci for CTS with p < 5 × 10
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.