ArticleNature communications2019
Protein and RNA dynamical fingerprinting.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed.
- On-chip terahertz metasensor for quantitative multi-component biomolecular identification.Light, science & applications · 2026Article
- Optimized Calibration of Terahertz Polarimetric Imaging Systems With Imperfect Polarizers for Accurate Jones-Matrix Mapping.Research square · 2026Article
- Vibrational contribution to the sub-terahertz dielectric response of kinesin and its hydration shell.Scientific reports · 2026Article
- Ultra-compact broadband terahertz spectroscopy sensor enabled by resonant-gradient metasurface.Nature communications · 2025Article
- Terahertz calorimetry spotlights the role of water in biological processes.Nature reviews. Chemistry · 2025Review
- A new horizon for neuroscience: terahertz biotechnology in brain research.Neural regeneration research · 2025Article
- Advances in Terahertz Biophysics and Chemistry.Research (Washington, D.C.) · 2025Review
- Ultra-Low Threshold Resonance Switching by Terahertz Field Enhancement-Induced Nanobridge.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A Reflective Terahertz Point Source Meta-Sensor with Asymmetric Meta-Atoms for High-Sensitivity Bio-Sensing.Biosensors · 2024Article
- A handheld polarimetric imaging device and calibration technique for accurate mapping of terahertz Stokes vectors.Scientific reports · 2024Article
- Exploring the Application of Terahertz Metamaterials Based on Metallic Strip Structures in Detection of Reverse Micelles.Biosensors · 2024Article
- Terahertz Radiation Modulates Neuronal Morphology and Dynamics Properties.Brain sciences · 2024Review
- High specificity THz metamaterial-based biosensor for label-free transcription factor detection in melanoma diagnostics.Scientific reports · 2023Article
- Nonthermal acceleration of protein hydration by sub-terahertz irradiation.Nature communications · 2023Article
- High-sensitivity polarization-independent terahertz Taichi-like micro-ring sensors based on toroidal dipole resonance for concentration detection of Aβ protein.Nanophotonics (Berlin, Germany) · 2023Article
- Terahertz phase shift sensing and identification of a chiral amino acid based on a protein-modified metasurface through the isoelectric point and peptide bonding.Biomedical optics express · 2023Article
- Proteomic Applications in Aquatic Environment Studies.Proteomes · 2022Review
- Cell Responsiveness to Physical Energies: Paving the Way to Decipher a Morphogenetic Code.International journal of molecular sciences · 2022Review
- The origin and impact of bound water around intrinsically disordered proteins.Biophysical journal · 2022Article
- Ultrasensitive, light-induced reversible multidimensional biosensing using THz metasurfaces hybridized with patterned graphene and perovskite.Nanophotonics (Berlin, Germany) · 2022Article
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Authors and funding
10 authors.
Funding
Abstract
Protein structural vibrations impact biology by steering the structure to functional intermediate states; enhancing tunneling events; and optimizing energy transfer. Strong water absorption and a broad continuous vibrational density of states have prevented optical identification of these vibrations. Recently spectroscopic signatures that change with functional state were measured using anisotropic terahertz microscopy. The technique however has complex sample positioning requirements and long measurement times, limiting access for the biomolecular community. Here we demonstrate that a simplified system increases spectroscopic structure to dynamically fingerprint biomacromolecules with a factor of 6 reduction in data acquisition time. Using this technique, polarization varying anisotropy terahertz microscopy, we show sensitivity to inhibitor binding and unique vibrational spectra for several proteins and an RNA G-quadruplex. The technique's sensitivity to anisotropic absorbance and birefringence provides rapid assessment of macromolecular dynamics that impact biology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.