ArticleAnnals of transplantation2019
Pure Red Cell Aplasia After Kidney Transplantation: Parvovirus B19 Culprit or Coincidence?
Article in Annals of transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Successful Treatment of Posttransplant Refractory Pure Red Cell Aplasia Following Parvovirus B19 Infection.Case reports in medicine · 2026Article
- A Rare Case of Parvovirus Infection Causing Pure Red Cell Aplasia in a Kidney-Pancreas Transplant Recipient.Nephrology (Carlton, Vic.) · 2025Article
- Resistant anemia in a kidney transplant recipient: Pure red cell aplasia due to parvovirus B19 infection.Qatar medical journal · 2024Article
- Relapsing anemia associated with parvovirus B19 infection in a kidney transplant recipient: A case report and review of the literature.Clinical case reports · 2023Article
- Recurrent parvovirus B19 infection-associated pure red cell aplasia in a kidney transplant patient.Korean journal of transplantation · 2020Article
- Parvovirus B19 Infection as a Cause of Refractory Anemia in Kidney Transplant Recipients: A Case Series.Indian journal of nephrologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Anemia is present even in long-term observation after kidney transplantation. Observational study results indicate the presence of chronic post-transplantation anemia in 1 in 3 recipients. An extreme form of erythroid line dysfunction is pure red cell aplasia (PRCA). It may be caused by immunosuppressive treatment per se or a side effect, opportunistic pathogen activation. Parvovirus B19 (PV B19) infection is quite likely the cause of refractory normocytic anemia in immunocompromised patients. CASE REPORT In this case report we discuss biological and clinical features of this phenomenon and the treatment strategies, based on 2 PRCA cases in kidney transplant recipients. Additionally, a systematic review of published reports of PV B19 related PRCA in kidney recipients is presented. CONCLUSIONS PV replication should be ruled out in cases of persistent and/or refractory anemia after kidney transplantation. The established first-line treatment of PRCA is passive immunization. Taking into account cost effectiveness, a decrease in immunosuppression load is reasonable under careful control of allograft function.
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