ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Partial Adaptation to the Value Range in the Macaque Orbitofrontal Cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Modeling value integration during decision making under uncertainty with the Florida and Georgia gambling task.Scientific reports · 2025Article
- Adaptive reward representations integrate expected uncertainty signals in orbitofrontal cortex.Science advances · 2025Article
- Article
- Multiattribute Decision-making in Macaques Relies on Direct Attribute Comparisons.Journal of cognitive neuroscience · 2024Article
- Recent Opioid Use Impedes Range Adaptation in Reinforcement Learning in Human Addiction.Biological psychiatry · 2024Article
- Article
- Efficiently irrational: deciphering the riddle of human choice.Trends in cognitive sciences · 2022Review
- Orbitofrontal cortex contributes to the comparison of values underlying economic choices.Nature communications · 2022Article
- Neuronal origins of reduced accuracy and biases in economic choices under sequential offers.eLife · 2022Article
- Foraging with the frontal cortex: A cross-species evaluation of reward-guided behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
- Review
- Subpopulations of neurons in lOFC encode previous and current rewards at time of choice.eLife · 2021Article
- Identifying identity and attributing value to attributes: reconsidering mechanisms of preference decisions.Current opinion in behavioral sciences · 2021Article
- Context-sensitive valuation and learning.Current opinion in behavioral sciences · 2021Article
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- Article
- The case against economic values in the orbitofrontal cortex (or anywhere else in the brain).Behavioral neuroscience · 2021Article
- Two sides of the same coin: Beneficial and detrimental consequences of range adaptation in human reinforcement learning.Science advances · 2021Article
- Article
- The Effect of Counterfactual Information on Outcome Value Coding in Medial Prefrontal and Cingulate Cortex: From an Absolute to a Relative Neural Code.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Values available for choice in different behavioral contexts can vary immensely. To compensate for this variability, neuronal circuits underlying economic decisions undergo adaptation. In orbitofrontal cortex (OFC), neurons encode the subjective value of offered and chosen goods in a quasilinear way. Previous experiments found that the gain of the encoding is lower when the value range is wider. However, the parameters OFC neurons adapted to remained unclear. Furthermore, previous studies did not examine additive changes in neuronal responses. Computational considerations indicate that these factors can directly impact choice behavior. Here we investigated how OFC neurons adapt to changes in the value range. We recorded from two male rhesus monkeys during a juice choice task. Each session was divided into two blocks of trials. In each block, juices were offered within a set range of values, and ranges changed between blocks. Across blocks, neuronal responses adapted to both the maximum and the minimum value, but only partially. As a result, the minimum neural activity was elevated in some value ranges relative to others. Through simulation of a linear decision model, we showed that increasing the minimum response increases choice variability, lowering the expected payoff. This effect is modulated by the balance between cells with positive and negative encoding. The presence of these two populations induces a non-monotonic relationship between the value range and choice efficacy, such that the expected payoff is highest for decisions in an intermediate value range.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.