Evidence map›Paper›PMID 30833359›Full record

ArticleJournal of bacteriology2019

The Lipoprotein NlpE Is a Cpx Sensor That Serves as a Sentinel for Protein Sorting and Folding Defects in the

Antoine Delhaye, Géraldine Laloux, Jean-François Collet

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Liganded LolCDE structures reveal a common substrate-LolE interaction guiding bacterial lipoprotein transport.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. ThemBio · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The BfmRS stress response protectsJournal of bacteriology · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. mBio · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Antoine Delhaye *de Duve Institute, Université Catholique de Louvain, Brussels, Belgium.ORCID 0000-0003-4682-6687
Géraldine Laloux *de Duve Institute, Université Catholique de Louvain, Brussels, Belgium geraldine.laloux@uclouvain.be jfcollet@uclouvain.be.ORCID 0000-0003-3230-1679
Jean-François Colletde Duve Institute, Université Catholique de Louvain, Brussels, Belgium geraldine.laloux@uclouvain.be jfcollet@uclouvain.be.ORCID 0000-0001-8069-7036
de Duve Institute · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The envelope of Gram-negative bacteria is a complex compartment that is essential for viability. To ensure survival of the bacterial cells in fluctuating environments, several signal transduction systems, called envelope stress response systems (ESRSs), exist to monitor envelope biogenesis and homeostasis. The Cpx two-component system is an extensively studied ESRS in

Indexed as

Protein FoldingBacterial Outer Membrane ProteinsBacterial ProteinsCell WallEscherichia coliEscherichia coli ProteinsLipoproteinsOxidative StressProtein BindingProtein Interaction MappingProtein KinasesProtein TransportBacterial Outer Membrane ProteinsBacterial ProteinsCpxA protein, E coliCpxR protein, BacteriaEscherichia coli ProteinsLipoproteinsNlpE protein, E coliProtein Kinasescell envelopeCpx stress responseenvelope biogenesisEscherichia colilipoproteinsNlpEtwo-component regulatory systems

Identifiers

PMID30833359
PMCPMC6482929
OpenAlexW2918907051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.