Evidence map›Paper›PMID 30833341›Full record

ArticleEMBO reports2019

Clipped histone H3 is integrated into nucleosomes of DNA replication genes in the human malaria parasite

Abril Marcela Herrera-Solorio, Shruthi Sridhar Vembar, Cameron Ross MacPherson, Daniela Lozano-Amado, Gabriela Romero Meza, Beatriz Xoconostle-Cazares, Rafael Miyazawa Martins, Patty Chen, Miguel Vargas, Artur Scherf and 1 more

Open access · hybridAbstract read
In one paragraph

Article in EMBO reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. ThemSphere · 2024
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. The tropical coralWellcome open research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Abril Marcela Herrera-SolorioDepartamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (IPN), Ciudad de Mexico, México.
Shruthi Sridhar VembarUnité Biologie des Interactions Hôte-Parasite, Département de Parasites et Insectes Vecteurs, Institut Pasteur, Paris, France.
Cameron Ross MacPhersonUnité Biologie des Interactions Hôte-Parasite, Département de Parasites et Insectes Vecteurs, Institut Pasteur, Paris, France.
Daniela Lozano-AmadoDepartamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (IPN), Ciudad de Mexico, México.
Gabriela Romero MezaDepartamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (IPN), Ciudad de Mexico, México.
Beatriz Xoconostle-CazaresDepartamento de Biotecnología y Bioingeniería, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (IPN), Ciudad de México, México.
Rafael Miyazawa MartinsUnité Biologie des Interactions Hôte-Parasite, Département de Parasites et Insectes Vecteurs, Institut Pasteur, Paris, France.
Patty ChenUnité Biologie des Interactions Hôte-Parasite, Département de Parasites et Insectes Vecteurs, Institut Pasteur, Paris, France.
Miguel VargasDepartamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (IPN), Ciudad de Mexico, México.
Artur ScherfUnité Biologie des Interactions Hôte-Parasite, Département de Parasites et Insectes Vecteurs, Institut Pasteur, Paris, France artur.scherf@pasteur.fr rohernan@cinvestav.mx.ORCID 0000-0003-2411-3328
Rosaura Hernández-RivasDepartamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (IPN), Ciudad de Mexico, México artur.scherf@pasteur.fr rohernan@cinvestav.mx.ORCID 0000-0002-5275-0730
Instituto Politécnico Nacional · MXCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-translational modifications of histone H3 N-terminal tails are key epigenetic regulators of virulence gene expression and sexual commitment in the human malaria parasite

Indexed as

DNA Replication5' Untranslated RegionsAmino Acid SequenceChromatin ImmunoprecipitationEctopic Gene ExpressionErythrocytesGene Expression RegulationHistonesHumansMalaria, FalciparumNucleosomesPlasmodium falciparumProtease InhibitorsProtein BindingProtein Interaction Domains and MotifsProteolysis5' Untranslated RegionsHistonesNucleosomesProtease Inhibitorsepigeneticshistone H3 clippingmalaria

Identifiers

PMID30833341
PMCPMC6446197
OpenAlexW2918875016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.