Evidence map›Paper›PMID 30832713›Full record

ArticleTrials2019

Jin's three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial.

Wenjia Lin, Xin-Lin Chen, Qi Chen, Junmao Wen, Xinghua Chen

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07559279 (The Potential Efficacy Of Jin's Three-Needle Technique Combined With Electroacupuncture In Managing Pain And Improving Cervical Active Range Of Motion In 104 Patients With Cervical Spondylosis And Blood Stasis Syndrome), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07559279 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Potential Efficacy Of Jin's Three-Needle Technique Combined With Electroacupuncture In Managing Pain And Improving Cervical Active Range Of Motion In 104 Patients With Cervical Spondylosis And Blood Stasis Syndrome: A Randomized, Single-Blind, Controlled Trial

TypeinterventionalSponsorUniversity of Medicine and Pharmacy at Ho Chi Minh CityRan2026 to 2026Enrolled104ConditionsPainArmsJin's Three-Needle Acupuncture therapy, Electroacupuncture, Active Movement Exercises
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wenjia LinGuangzhou University of Traditional Chinese Medicine, Guangzhou, 510405, China.
Xin-Lin ChenSchool of Basic Medical Science, Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510006, China.
Qi ChenGuangzhou University of Traditional Chinese Medicine, Guangzhou, 510405, China.
Junmao WenGuangzhou University of Traditional Chinese Medicine, Guangzhou, 510405, China.
Xinghua ChenThe First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510405, China. xinghuac@outlook.com.ORCID http://orcid.org/0000-0002-8398-8354
Guangzhou University · CN

Funding

Guangdong Science and Technology Department 2016A020215139National Natural Science Foundation of China 81774451Natural Science Foundation of Guangdong Province 2017A030313827
6 · The paper itself

Abstract

backgroundWith an unclear pathomechanism, no confirmed treatment regimen has been established for chronic fatigue syndrome (CFS). Acupuncture is applied as an alternative therapy for CFS. As a kind of acupuncture therapy, Jin's three-needle acupuncture (JTN) has been applied to treat CFS. However, few large-sample randomised controlled trials on JTN treatment for CFS have been reported. We designed this study to evaluate the efficacy and safety of JTN treatment for CFS. METHOD/

designThis study is a multicentre, single-blind, randomised controlled trial. Patients who meet the inclusion criteria will be recruited and randomly assigned to either the JTN treatment group or the basic acupuncture group. Both interventions will be conducted for five consecutive days per week and last for 2 weeks. The primary outcome is the effective rate based on the 14-item Fatigue Scale (FS-14) score. Other outcome measures include the Fatigue Assessment Scale (FAI), the Depression Status Inventory (DSI), and the Self-rating Anxiety Scale (SAS). Plasma adrenocorticotropic hormone (ACTH), plasma cortisol, and serum levels of IL-2 and IFN-γ will also be measured in this study. Adverse events will be observed and recorded for the safety evaluation. DISCUSSION: This study may help to identify the efficacy and safety of JTN acupuncture treatment for CFS.

trial registrationChinese Clinical Trial Registry, ID: ChiCTR-IOR-17011009 . Registered on 29 March 2017.

Indexed as

Acupuncture PointsAcupuncture TherapyAdultBiomarkersChinaFatigue Syndrome, ChronicFemaleHumansMaleMiddle AgedMulticenter Studies as TopicNeedlesRandomized Controlled Trials as TopicSingle-Blind MethodSurveys and QuestionnairesTime FactorsBiomarkersAcupunctureChronic fatigue syndromeJin’s three-needle techniqueRandomised controlled trial

Identifiers

PMID30832713
PMCPMC6399952
OpenAlexW2923568899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.