ArticleBMC veterinary research2019
Immune related genes as markers for monitoring health status of honey bee colonies.
Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Diet Quality Shapes Metabolic and Immune Transcriptional Responses of Honey Bees Under Acute Heat Stress.Insects · 2026Article
- From Pollen to Pathogen Defense: How Pollen Chemical Quality Impacts Deformed Wing Virus Infection and Survival in Honey Bees.Viruses · 2026Review
- Deformed Wing Virus infection induces immunosuppression and gut dysbiosis in honey bees.Animal microbiome · 2026Article
- Superinfection Exclusion in Neotropical Honey Bees May Block DWV-B, an Emerging Infectious Disease Variant of Deformed Wing Virus.Evolutionary applications · 2025Article
- Advanced Research on Biological Properties-A Study on the Activity of theInternational journal of molecular sciences · 2025Article
- Molecular Assessment of Genes Linked to Honeybee Health Fed with Different Diets in Nuclear Colonies.Insects · 2025Article
- Article
- Honeybee proteins in Saudi honeys: A shotgun gel-free proteomic study.Food chemistry: X · 2025Article
- Climate change-induced stress in the honey beeFrontiers in physiology · 2025Review
- Article
- Effects of natural treatments on the varroa mite infestation levels and overall health of honey bee (Apis mellifera) colonies.PloS one · 2024Article
- A field realistic model to assess the effects of pesticides residues and adulterants on honey bee gene expression.PloS one · 2024Article
- Monitoring Immune Modulation in Season Population: Identifying Effects and Markers Related toBiomolecules · 2023Article
- Review
- The Insecticide Imidacloprid DecreasesInsects · 2022Article
- Bee Stressors from an Immunological Perspective and Strategies to Improve Bee Health.Veterinary sciences · 2022Review
- Contact varroacidal efficacy of lithium citrate and its influence on viral loads, immune parameters and oxidative stress of honey bees in a field experiment.Frontiers in physiology · 2022Article
- Effects ofInsects · 2021Article
- Transcriptome-level assessment of the impact of deformed wing virus on honey bee larvae.Scientific reports · 2021Article
- Improved mitochondrial function corrects immunodeficiency and impaired respiration in neonicotinoid exposed bumblebees.PloS one · 2021Article
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Authors and funding
5 authors.
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Abstract
backgroundHoney bee population decline threatens the beekeeping sector, agriculture and global biodiversity. Early detection of colony mortality may facilitate rapid interventions to contain and prevent mortality spread. Among others, deformed wing virus (DWV) is capable of inducing colony losses, especially when combined with Varroa destructor mite. Since the bee immune system plays a crucial role in ensuring that bees are able to face these pathogens, we explored whether expression of immune genes could serve as biomarkers of colony health.
resultsHerein, we describe a preliminary immunological marker composed of two immune genes (relish and defensin), which provide insight on honey bee antiviral defense mechanism. Of the tested genes, relish expression correlated with the presence of DWV-Varroa complex, while decreased defensin expression correlated with poor resistance to this complex.
conclusionsThe monitoring of these genes may help us to better understand the complex physiology of honey bees's immune system and to develop new approaches for managing the health impacts of DWV infection and varroa infestation in the field.
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