ReviewLife (Basel, Switzerland)2019
How Prebiotic Chemistry and Early Life Chose Phosphate.
Review in Life (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 64 citations in OpenAlex.
- From Mineral Surfaces to Peptides: Hydroxyapatite-Based Platforms for Surface-Mediated Prebiotic Synthesis.International journal of molecular sciences · 2026Review
- Cryogenic Vibrational Spectroscopy of the Deprotonated Dimer of Phosphoric Acid.The journal of physical chemistry. A · 2026Article
- Magmatic immiscibility provides phosphate for prebiotic chemistry.Science advances · 2025Article
- Anion-π interaction-induced phase separation as a prebiotic pathway to oxygenation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes.Chembiochem : a European journal of chemical biology · 2025Review
- Large closed-basin lakes sustainably supplied phosphate during the origins of life.Science advances · 2025Article
- Heat flows solubilize apatite to boost phosphate availability for prebiotic chemistry.Nature communications · 2025Article
- Investigation of the Proton-Bound Dimer of Dihydrogen Phosphate and Formate Using Infrared Spectroscopy in Helium Droplets.The journal of physical chemistry. A · 2024Article
- Multiphosphorylation-Dependent Recognition of Anti-pS2 Antibodies against RNA Polymerase II C-Terminal Domain Revealed by Chemical Synthesis.Journal of the American Chemical Society · 2024Article
- A Prebiotic Precursor to Life's Phosphate Transfer System with an ATP Analog and Histidyl Peptide Organocatalysts.Journal of the American Chemical Society · 2024Article
- Prebiotic Syntheses of Organophosphorus Compounds from Reduced Source of Phosphorus in Non-Aqueous Solvents.Life (Basel, Switzerland) · 2023Article
- On the potential roles of phosphorus in the early evolution of energy metabolism.Frontiers in microbiology · 2023Review
- The limits of metabolic heredity in protocells.Proceedings. Biological sciences · 2022Article
- A prebiotic basis for ATP as the universal energy currency.PLoS biology · 2022Article
- Lessons from protozoans: Phosphate sensing and polyphosphate storage in fungi.PLoS pathogens · 2022Article
- Diamidophosphate (DAP): A Plausible Prebiotic Phosphorylating Reagent with a Chem to BioChem Potential?Chembiochem : a European journal of chemical biology · 2021Review
- A physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations.Nature communications · 2021Article
- From organic and inorganic phosphates to valvular and vascular calcifications.Cardiovascular research · 2021Review
- The Grayness of the Origin of Life.Life (Basel, Switzerland) · 2021Article
- Chiral Amplification of Phosphoramidates of Amines and Amino Acids in Water.Angewandte Chemie (International ed. in English) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
The very specific thermodynamic instability and kinetic stability of phosphate esters and anhydrides impart them invaluable properties in living organisms in which highly efficient enzyme catalysts compensate for their low intrinsic reactivity. Considering their role in protein biosynthesis, these properties raise a paradox about early stages: How could these species be selected in the absence of enzymes? This review is aimed at demonstrating that considering mixed anhydrides or other species more reactive than esters and anhydrides can help in solving the paradox. The consequences of this approach for chemical evolution and early stages of life are analysed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.