Evidence map›Paper›PMID 30832263›Full record

ArticleCancers2019

Usefulness and Limitations of Comprehensive Characterization of mRNA Splicing Profiles in the Definition of the Clinical Relevance of

Elisa Gelli, Mara Colombo, Anna Maria Pinto, Giovanna De Vecchi, Claudia Foglia, Sara Amitrano, Valeria Morbidoni, Valentina Imperatore, Siranoush Manoukian, Margherita Baldassarri and 11 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. International journal of molecular sciences · 2025
    Review
  2. Clinically SignificantCancers · 2024
    Article
  3. TheInternational journal of molecular sciences · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Cancers · 2021
    Article
  8. Characterization of SynonymousFrontiers in oncology · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Elisa GelliMedical Genetics, University of Siena, 53100 Siena, Italy. elisa.gelli@student.unisi.it.
Mara ColomboUnit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy. Mara.Colombo@istitutotumori.mi.it.ORCID 0000-0001-5465-354X
Anna Maria PintoMedical Genetics, University of Siena, 53100 Siena, Italy. annamaria.pinto@dbm.unisi.it.ORCID 0000-0001-6259-6901
Giovanna De VecchiUnit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy. giovanna.devecchi@cogentech.it.
Claudia FogliaUnit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy. Claudia.Foglia@istitutotumori.mi.it.
Sara AmitranoGenetica medica Azienda Ospedaliera Universitaria Senese, 53100 Siena, Italy. sara.amitrano@dbm.unisi.it.
Valeria MorbidoniDepartment of Woman and Child Health, University of Padova, 35128 Padova, Italy. valeria.morbidoni@gmail.com.
Valentina ImperatoreMedical Genetics, University of Siena, 53100 Siena, Italy. va.imperatore@gmail.com.
Siranoush ManoukianUnit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy. Siranoush.Manoukian@istitutotumori.mi.it.
Margherita BaldassarriGenetica medica Azienda Ospedaliera Universitaria Senese, 53100 Siena, Italy. margherita.baldassarri@dbm.unisi.it.
Caterina Lo RizzoGenetica medica Azienda Ospedaliera Universitaria Senese, 53100 Siena, Italy. lorizzo2@unisi.it.
Lorenza CataniaMedical Genetics, University of Siena, 53100 Siena, Italy. catania4@student.unisi.it.
Elisa FrullantiMedical Genetics, University of Siena, 53100 Siena, Italy. elisa.frullanti@dbm.unisi.it.
Enrico TagliaficoDepartment of Medical and Surgical Science, Center for Genome Research, University of Modena and Reggio Emilia, 41125 Modena, Italy. enrico.tagliafico@unimore.it.
Laura CortesiDepartment of Oncology and Haematology, Azienda Ospedaliero-Universitaria Policlinico, University of Modena and Reggio Emilia, 41124 Modena, Italy. cortesi.laura@aou.mo.it.
Federica SpaggiariDepartment of Oncology and Haematology, Azienda Ospedaliero-Universitaria Policlinico, University of Modena and Reggio Emilia, 41124 Modena, Italy. hbc@unimore.it.
Maria Antonietta MencarelliGenetica medica Azienda Ospedaliera Universitaria Senese, 53100 Siena, Italy. mariaantonietta.mencarelli@unisi.it.ORCID 0000-0001-5131-3718
Eva TrevissonDepartment of Woman and Child Health, University of Padova, 35128 Padova, Italy. eva.trevisson@unipd.it.
Paolo RadiceUnit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy. Paolo.Radice@istitutotumori.mi.it.
Alessandra RenieriMedical Genetics, University of Siena, 53100 Siena, Italy. alessandra.renieri@unisi.it.ORCID 0000-0002-0846-9220
Francesca ArianiMedical Genetics, University of Siena, 53100 Siena, Italy. francesca.ariani@unisi.it.
University of Siena · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITAzienda Ospedaliera Universitaria Senese · ITUniversity of Modena and Reggio Emilia · ITUniversity of Padua · IT

Funding

5x1000 Fondazione IRCCS Istituto Nazionale Tumori INT-Institutional strategic projects '5x1000'Associazione Italiana per la Ricerca sul Cancro IG2014 no.15547
6 · The paper itself

Abstract

Highly penetrant variants of

Indexed as

BRCAmRNA analysissplicingVUS

Identifiers

PMID30832263
PMCPMC6468917
OpenAlexW2918428936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.