ArticleMolecules (Basel, Switzerland)2019
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
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In one paragraph
Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 85 citations in OpenAlex.
- Optimization of enzyme-assisted extraction of polyphyllins from paris polyphylla var. yunnanensis rhizomes using response surface methodology.Scientific reports · 2026Article
- Polyphyllins ameliorate imiquimod-induced psoriatic skin barrier disruption and lesions in mice by inhibiting inflammatory infiltration with accelerated recovery effects.Frontiers in immunology · 2026Article
- Voacangine mitigates lipopolysaccharide-produced sepsis-triggered acute lung injury via inhibition of PERK/PI3K and TLR4/NF-кB/IL-1β pathways in mice.Journal of molecular histology · 2025Article
- Berberine's Impact on Apoptosis, Proliferation, Uptake Efficiency, and Nanoparticle-Based Therapy in DBTRG Cells.ACS nanoscience Au · 2025Article
- Polyphyllin VII promotes hepatic stellate cell ferroptosis via the HIC1/CX3CL1/GPX4 axis.Journal of pharmaceutical analysis · 2025Article
- Polyphyllin VII enhances the sensitivity of endometrial carcinoma cells to medroxyprogesterone acetate through upregulating miR‑33a‑5p expression.Oncology letters · 2025Article
- Review
- Regulation of anti-tumour effects of Paris polyphylla saponins via ROS: molecular mechanisms and therapeutic potentials.Frontiers in pharmacology · 2025Review
- The role ofHeliyon · 2024Review
- Study on Synthesis and Regulation of PPVI and PPVII inMetabolites · 2024Article
- Anti-inflammatory and analgesic properties of Polyphyllin VI revealed by network pharmacology and RNA sequencing.Purinergic signalling · 2024Article
- Study on Anti-fatigue Effects and Mechanisms of Polysaccharide from Paris polyphylla.Doklady. Biochemistry and biophysics · 2024Article
- Saponins ofMolecules (Basel, Switzerland) · 2024Review
- Article
- Rhizoma Paridis saponins attenuate Gram-negative bacteria-induced inflammatory acne by binding to KEAP1 and modulating Nrf2 and MAPK pathways.Journal of cellular and molecular medicine · 2024Article
- Comparison of the inhibition effects of naringenin and its glycosides on LPS-induced inflammation in RAW 264.7 macrophages.Molecular biology reports · 2024Article
- Paris saponin VII reverses resistance to PARP inhibitors by regulating ovarian cancer tumor angiogenesis and glycolysis through the RORα/ECM1/VEGFR2 signaling axis.International journal of biological sciences · 2024Article
- Protective Effects of Sophoraflavanone G by Inhibiting TNF-α-Induced MMP-9-Mediated Events in Brain Microvascular Endothelial Cells.International journal of molecular sciences · 2023Article
- Anti-Inflammatory and Antioxidant Properties of β-Sitosterol in Copper Sulfate-Induced Inflammation in Zebrafish (Antioxidants (Basel, Switzerland) · 2023Article
- Effects of Organophosphate-Degrading Bacteria on the Plant Biomass, Active Medicinal Components, and Soil Phosphorus Levels ofPlants (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Chao ZhangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing 100029, China. zhangchao_0213@126.com.
Chaoying LiSchool of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun 130117, China. chaoying_li@126.com.
Xuejing JiaState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China. jiaxjsicau@gmail.com.
Kai WangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China. wangkai6648@gmail.com.
Yanbei TuState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China. tuyanbei1992@163.com.
Rongchun WangKey Laboratory for Drug Screening Technology of Shandong Academy of Sciences, Shandong Provincial Key Laboratory for Biosensor, Biology Institute of Shandong Academy of Sciences, Jinan 250014, China. 1wangrongchun@163.com.
Kechun LiuKey Laboratory for Drug Screening Technology of Shandong Academy of Sciences, Shandong Provincial Key Laboratory for Biosensor, Biology Institute of Shandong Academy of Sciences, Jinan 250014, China. hliukch@sdas.org.
Tao LuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing 100029, China. taolu@bucm.edu.cn.
Chengwei HeState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China. chengweihe@umac.mo.ORCID 0000-0003-4701-2984
University of Macau · MOBeijing University of Chinese Medicine · CNBiology Institute of Shandong Academy of Sciences · CNChangchun University of Chinese Medicine · CN
Funding
Macao Science and Technology Development Fund 041/2016/AMacao Science and Technology Development Fund 070/2017/A2National Natural Science Foundation of China 81273883Research Fund of the University of Macau MYRG2018-00176-ICMS
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsAnti-Inflammatory AgentsCyclooxygenase 2DinoprostoneDisease Models, AnimalEnzyme-Linked Immunosorbent AssayGene Expression RegulationHumansInflammationInterleukin-1betaInterleukin-6LipopolysaccharidesMAP Kinase Kinase 1MiceNF-kappa BNitric OxideAnti-Inflammatory AgentsCyclooxygenase 2DinoprostoneInterleukin-1betaInterleukin-6LipopolysaccharidesMAP Kinase Kinase 1NF-kappa BNitric OxideNitric Oxide Synthase Type IIpolyphyllin VIISaponinsTumor Necrosis Factor-alphaanti-inflammationmacrophagemicepolyphyllin VIIzebrafish
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.