Evidence map›Paper›PMID 30832204›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Non-Mammalian Prdx6 Enzymes (Proteins with 1-Cys Prdx Mechanism) Display PLA₂ Activity Similar to the Human Orthologue.

Renata Bannitz-Fernandes, Rogério Aleixo-Silva, João Paulo Silva, Chandra Dodia, Jose Pablo Vazquez-Medina, Jian-Qin Tao, Aron Fisher, Luis Netto

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. The Human PathogenFrontiers in cellular and infection microbiology · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Renata Bannitz-FernandesDepartamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo SP 05508-090, Brazil. bannitzfernandes@gmail.com.ORCID 0000-0001-7512-8891
Rogério Aleixo-SilvaDepartamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo SP 05508-090, Brazil. rlaleixosilva@gmail.com.
João Paulo SilvaDepartamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo SP 05508-090, Brazil. silvajpn7@gmail.com.
Chandra DodiaDepartment of Physiology, Institute for Environmental Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. cdodia@pennmedicine.upenn.edu.
Jose Pablo Vazquez-MedinaDepartment of Physiology, Institute for Environmental Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. jpv-m@berkeley.edu.ORCID 0000-0003-1014-5214
Jian-Qin TaoDepartment of Physiology, Institute for Environmental Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. taoj@mail.med.upenn.edu.
Aron FisherDepartment of Physiology, Institute for Environmental Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. abf@upenn.edu.
Luis NettoDepartamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo SP 05508-090, Brazil. nettoles@ib.usp.br.ORCID 0000-0002-4250-9177
Universidade de São Paulo · BRUniversity of Pennsylvania · US

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 130255/2016-5Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/07937-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2016/12248-5National Institutes of Health R01-HL102016
6 · The paper itself

Abstract

Mammalian peroxiredoxin class 6 (Prdx6) are bifunctional enzymes. Non-mammalian Prdx6 enzymes display Cys-based peroxidase activity, but to date their putative phospholipase A₂ (PLA₂ activities) has not been experimentally investigated. Initially, we observed that five non-mammalian Prdx6 enzymes (enzymes from

Indexed as

1-Cys PrdxPeroxiredoxinPLA2 activityPrdx6

Identifiers

PMID30832204
PMCPMC6466579
OpenAlexW2916969251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.