Evidence map›Paper›PMID 30831142›Full record

SynthesisImmunology letters2019

Inflammasomes and their roles in the pathogenesis of viral hepatitis and their related complications: An updated systematic review.

Maryam Dadmanesh, Mohammad Mehdi Ranjbar, Khodayar Ghorban

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Immunology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06502808 (The Effect of Hyperbaric Oxygen Therapy on Oxidative Stress and Inflammation in Patients With Diabetic Foot Ulcers), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06502808 completednot on this map

The Effect of Hyperbaric Oxygen Therapy on Oxidative Stress and Inflammation in Patients With Diabetic Foot Ulcers

Typeobservational_patient_registrySponsorNational Polytechnic Institute, MexicoRan2019 to 2020Enrolled15ConditionsDiabetic Foot Ulcer NeuropathicArmsHyperbaric oxygen therapy
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. NLRP3 Inflammasomes: Dual Function in Infectious Diseases.Journal of immunology (Baltimore, Md. : 1950) · 2024
    Review
  7. NLRP3 Inflammasome in Acute and Chronic Liver Diseases.International journal of molecular sciences · 2024
    Review
  8. Review
  9. Chemotherapy: a double-edged sword in cancer treatment.Cancer immunology, immunotherapy : CII · 2022
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Maryam DadmaneshInfectious Diseases Research Center, Aja University of Medical Sciences, Tehran, Iran; Department of Infectious Diseases, Medical School, Aja University of Medical Sciences, Tehran, Iran.
Mohammad Mehdi RanjbarRazi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran. Electronic address: mm.ranjbar@rvsri.ac.ir.
Khodayar GhorbanInfectious Diseases Research Center, Aja University of Medical Sciences, Tehran, Iran; Department of Immunology, Medical School, Aja University of Medical Sciences, Tehran, Iran. Electronic address: kh.ghorban@ajaums.ac.ir.
Aja University of Medical Sciences · IRAgricultural Research & Education Organization · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammasomes are a set of innate receptors which are the responsible molecules for activation of pro-interleukin (IL)-1β and IL-18 and induction of inflammation. Due to the key roles of the inflammasomes in the induction of inflammation, it has been hypothesized that the molecules may be the main parts of immune responses against viral infections and the tissue damage. Because some cases of viral hepatitis infections, including hepatitis B and C, are diagnosed as chronic and may be associated with various complications such as liver cirrhosis and hepatocellular carcinoma (HCC), several studies focused on the roles played by the inflammation on the pathogenesis of viral hepatitis. Based on the roles played by inflammasomes in induction of inflammation, it has been hypothesized that inflammasomes may be the main parts of the puzzle of the viral hepatitis complications. This article reviews the roles of the inflammasomes in the pathogenesis of hepatitis B and C viral infections and their complications, liver cirrhosis, and HCC.

Indexed as

Disease SusceptibilityAnimalsBiomarkersCytokinesHepacivirusHepatitis B virusHepatitis, Viral, HumanHost-Pathogen InteractionsHumansImmunity, InnateInflammasomesLiver CirrhosisBiomarkersCytokinesInflammasomesHepatitis B virusHepatitis C virusHepatocellular carcinomaInflammasomesLiver cirrhosis

Identifiers

PMID30831142
PMCPMC7112799
OpenAlexW2918193682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.