SynthesisAddiction (Abingdon, England)2019
Prevalence of fetal alcohol spectrum disorder among special subpopulations: a systematic review and meta-analysis.
Synthesis in Addiction (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 4 syntheses or guidelines pooled it, 223 citations in OpenAlex.
- Systematic review of health and disease in Ukrainian children highlights poor child health and challenges for those treating refugees.Acta paediatrica (Oslo, Norway : 1992) · 2022Pooled it
- Oral and written communication skills of adolescents with prenatal alcohol exposure (PAE) compared with those with no/low PAE: A systematic review.International journal of language & communication disorders · 2021Pooled it
- A Systematic Review of Interventions to Improve Mental Health and Substance Use Outcomes for Individuals with Prenatal Alcohol Exposure and Fetal Alcohol Spectrum Disorder.Alcoholism, clinical and experimental research · 2020Pooled it
- Prevalence of fetal alcohol spectrum disorder among special subpopulations: a systematic review and meta-analysis.Addiction (Abingdon, England) · 2019Pooled it
- Families Moving Forward Connect mHealth Intervention for Caregivers of Children With Fetal Alcohol Spectrum Disorders: Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- An economic analysis of Native CHOICES.Journal of substance use and addiction treatment · 2026Trial
- Developmental Trajectory of Auditory Brainstem Deficits in a Mouse Model of Fetal Alcohol Spectrum Disorders.Developmental neurobiology · 2026Article
- Increasing Access to FASD-Informed Care: Bringing an Adapted Intervention to Mental Health Providers.Evidence-based practice in child and adolescent mental health · 2026Article
- Alcohol Metabolism into Acetaldehyde in Developing Cerebral Arteries.International journal of molecular sciences · 2026Article
- A National Fetal Alcohol Spectrum Disorders Learning Collaborative for Pediatric Care Teams.Journal of pediatrics. Clinical practice · 2026Article
- Caregiver-reported evaluation for and diagnosis of fetal alcohol spectrum disorders in the United States.Drug and alcohol dependence · 2026Article
- Evaluating the role of strengths and protective factors for youth with FASD and criminal legal system involvement: a scoping review.Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2026Article
- Prenatal Alcohol Exposure and Mitochondrial Function in the Brain.Advances in experimental medicine and biology · 2026Review
- A content analysis of caregiver perspectives on strengths and protective factors in youth with FASD and criminal legal system involvement.Health & justice · 2025Article
- Ethanol Exposure Increases Oxygen Consumption by Developing Cerebral Arteries in a Trimester-, Concentration- and Sex-Dependent Manner.Biomolecules · 2025Article
- Article
- The Relationship Between Prenatal Alcohol Exposure and Infant/Child-Caregiver Attachment: A Scoping Review.Children (Basel, Switzerland) · 2025Review
- Prevalence of Fetal Alcohol Spectrum Disorders: A Pilot Study in Western Sweden.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Estimating the Prevalence of Fetal Alcohol Spectrum Disorder in Australia.Drug and alcohol review · 2025Article
- Ethanol downregulates gastrula gene expression and cell movement, causing symptoms of foetal alcohol spectrum disorders.Biology open · 2025Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo collate prevalence estimates of fetal alcohol spectrum disorder (FASD) among special subpopulations (defined by service use).
designSystematic literature review and meta-analysis of original, quantitative studies published between 1 November 1973 and 1 December 2018. The PRISMAGATHER were adhered to. The review protocol [includes FASD prevalence in (a) general and (b) special populations] is available on PROSPERO (registration number: CRD42016033837). Prevalence estimates were collated for all included studies with country-, disorder- [FASD and fetal alcohol syndrome (FAS)] and population-specific random-effects meta-analyses conducted. SETTING AND
participantsA number of service-defined subpopulations globally (see Findings). MEASUREMENTS: The main outcome was the prevalence of FASD among special subpopulations. The critical appraisal of each study was conducted using the Joanna Briggs Institute tool.
findingsWe identified 69 studies, comprising 6177 individuals diagnosed with FASD from 17 countries: Australia (n = 5), Brazil (n = 2), Canada (n = 15), Chile (n = 4), eastern Europe (Moldova, Romania and Ukraine; n = 1), Germany (n = 1), Israel (n = 1), Lithuania (n = 1), the Netherlands (n = 1), Poland (n = 1), Russia (n = 9), South Korea (n = 1), Spain (n = 1), Sweden (n = 1) and United States (n = 25). FAS and FASD prevalence rates were collated for the following five subpopulations: children in care, correctional, special education, specialized clinical and Aboriginal populations. The estimated prevalence of FASD in these special subpopulations was 10-40 times higher compared with the 7.7 per 1000 (95% confidence interval = 4.9-11.7) global FASD prevalence in the general population.
conclusionsGlobal subpopulations of children in care, correctional, special education, specialized clinical and Aboriginal populations have a significantly higher prevalence of fetal alcohol spectrum disorder compared with the general population, which poses a substantial global health problem.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.