Evidence map›Paper›PMID 30830753›Full record

ArticleBiochemistry2019

Structural Basis of Lysosomal Phospholipase A

Renee A Bouley, Vania Hinkovska-Galcheva, James A Shayman, John J G Tesmer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Renee A BouleyLife Sciences Institute and Department of Pharmacology , University of Michigan , Ann Arbor , Michigan 48109 , United States.ORCID 0000-0002-1358-0994
Vania Hinkovska-GalchevaDepartment of Internal Medicine, University of Michigan Medical School , University of Michigan , Ann Arbor , Michigan 48109 , United States.
James A ShaymanDepartment of Internal Medicine, University of Michigan Medical School , University of Michigan , Ann Arbor , Michigan 48109 , United States.
John J G TesmerDepartments of Biological Sciences and of Medicinal Chemistry & Molecular Pharmacology , Purdue University , West Lafayette , Indiana 47907 , United States.
University of Michigan · USPurdue University West Lafayette · US

Funding

Structure, function, and inhibition of G protein-coupled receptor kinasesR01HL071818 · NHLBI · UNIVERSITY OF TEXAS AUSTIN · PI TESMER, JOHN · 2004 to 2023
$7.1M
Structural Studies of Galphaq and Its Complexes at the Cell MembraneR01HL086865 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TESMER, JOHN · 2007 to 2015
$3.0M
Structure and Function of the LPLA2/LCAT Acyltransferase FamilyR01HL122416 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TESMER, JOHN · 2015 to 2018
$1.9M
GPCR - Linked RhoGEFs in Tumor Growth and MetastasisR01CA221289 · NCI · PURDUE UNIVERSITY · PI TESMER, JOHN · 2018 to 2022
$1.9M
NCI NIH HHS R01 CA221289NHLBI NIH HHS R01 HL071818NHLBI NIH HHS R01 HL086865NHLBI NIH HHS R01 HL122416
6 · The paper itself

Abstract

Lysosomal phospholipase A

Indexed as

AcyltransferasesAnimalsBinding SitesCatalytic DomainEnzyme StabilityHEK293 CellsHumansHydrogen-Ion ConcentrationLysosomesMiceMolecular Docking SimulationPhospholipases A2Protein BindingProtein ConformationZincAcyltransferasesphospholipase A2, group XVPhospholipases A2Zinc

Identifiers

PMID30830753
PMCPMC6677152
OpenAlexW2920257494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.