Observational studyWorld journal of pediatrics : WJP2019
Impact of preterm birth and low birth weight on medical conditions, medication use and mortality among neonates: a prospective observational cohort study.
Observational study in World journal of pediatrics : WJP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Effect of Preterm Birth on the Risk of Adverse Perinatal and Neonatal Outcomes in Ethiopia: A Systematic Review and Meta-Analysis.Inquiry : a journal of medical care organization, provision and financingPooled it
- Feasibility of integration of a novel bCPAP system into the NICU of a Public Referral Hospital in Mysuru, India.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Feeding and swallowing difficulties in previously hospitalised premature infants in the neonatal intensive care unit: Perspectives from South African caregivers.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2025Article
- Prevalence of Low Birth Weight and Its Developmental Vulnerability Among Infants in Nepal: A Critical Review of the Literature and Future Recommendations.JNMA; journal of the Nepal Medical Association · 2025Review
- Progression of gut microbiome in preterm infants during the first three months.Scientific reports · 2025Article
- Neonatal Mortality Rate and Its Determinants: A Community-Based Panel Study in Ethiopia.Frontiers in pediatrics · 2022Article
- Risk factors for respiratory assistance in premature infants.Experimental and therapeutic medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a paucity of studies conducted in India on neonatal outcomes of preterm birth and low birth weight. Hence, we aimed to assess the impact of preterm birth and low birth weight on medical conditions, medication use and mortality among neonates.
methodsA prospective observational cohort study was conducted at the neonatal intensive care unit (NICU) over a period of 9 months. Neonates of either sex, admitted to NICU and who received at least one medication were enrolled in the study. Perinatal and demographic data, reason(s) for NICU admission, diagnoses, medications prescribed, medication-related problems, discharge status and the direct medical cost were documented and analyzed.
resultsFour hundred and five neonates were included in the study: 60.5% were boys, 32.7% were preterm and 44.2% were born underweight. Neonatal sepsis (n = 125, 16.7%), unconjugated hyperbilirubinemia (n = 83, 11.1%) and respiratory distress syndrome (n = 62, 8.3%) were the most common medical conditions and were significantly more common among preterm and underweight neonates. Nearly half of the medications prescribed were anti-infectives for systemic use (n = 1310, 47.4%). The mean number of medications received by neonates increased from term to extremely preterm (5.2-15.0) and normal birth weight to extremely low birth weight (5.0-14.9). Mortality rate was significantly higher among extremely preterm (66.7%), and very preterm (15.2%) neonates compared to term (2.9%) neonates. The median direct medical cost for NICU admission was INR 21,430 (USD 331).
conclusionMedical conditions, medications prescribed and mortality rate were significantly higher among preterm and underweight neonates admitted to NICU.
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