Evidence map›Paper›PMID 30830508›Full record

ArticleEJNMMI research2019

Interobserver variability of image-derived arterial blood SUV in whole-body FDG PET.

Frank Hofheinz, Jens Maus, Sebastian Zschaeck, Julian Rogasch, Georg Schramm, Liane Oehme, Ivayla Apostolova, Jörg Kotzerke, Jörg van den Hoff

Abstract read
In one paragraph

Article in EJNMMI research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Radioembolization-Induced Changes in Hepatic [Diagnostics (Basel, Switzerland) · 2022
    Article
  3. Article
  4. Reliable quantification ofEuropean journal of nuclear medicine and molecular imaging · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Frank HofheinzPET Center, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstraße 400, Dresden, Germany. f.hofheinz@hzdr.de.ORCID http://orcid.org/0000-0001-8016-4643
Jens MausPET Center, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstraße 400, Dresden, Germany.
Sebastian ZschaeckCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiation Oncology, Berlin, Germany.
Julian RogaschCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Nuclear Medicine, Berlin, Germany.
Georg SchrammDivision of Nuclear Medicine, Department of Imaging and Pathology, KU/UZ Leuven, Leuven, Belgium.
Liane OehmeKlinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Carl Gustav Carus, Dresden, Germany.
Ivayla ApostolovaZentrum für Radiologie und Endoskopie, Abteilung für Nuklearmedizin, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Jörg KotzerkeKlinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Carl Gustav Carus, Dresden, Germany.
Jörg van den HoffPET Center, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstraße 400, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundToday, the standardized uptake value (SUV) is essentially the only means for quantitative evaluation of static [

methodsFDG PET/CT scans from 83 patients (72 male, 11 female) with non-small cell lung cancer (N = 46) or head and neck cancer (N = 37) were included. BSUV was determined by 8 individuals, each applying a dedicated delineation tool for the BSUV determination in the aorta. Two of the observers applied two further tools. Altogether, five different delineation tools were used. With each used tool, delineation was performed for the whole patient group, resulting in 12 distinct observations per patient. Intersubject variability of BSUV determination was assessed using the fractional deviations for the individual patients from the patient group average and was quantified as standard deviation (SD

resultsInterobserver variability in the pooled data amounts to RMS = 2.8% and is much smaller than the intersubject variability of BSUV (SD

conclusionThe present investigation demonstrates that the image-based manual determination of BSUV in the aorta is sufficiently reproducible across different observers and delineation tools which is a prerequisite for accurate SUR determination. This finding is in line with the already demonstrated superior prognostic value of SUR in comparison to SUV in the first clinical studies.

Indexed as

Blood SUVFDGPETQuantificationSURSUV

Identifiers

PMID30830508
PMCPMC6399366

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