ReviewMetabolomics : Official journal of the Metabolomic Society2019
Optimizing 1D
Review in Metabolomics : Official journal of the Metabolomic Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Application ofPlants (Basel, Switzerland) · 2026Article
- Article
- Comparative metabolomics reveals how the severity of predation by the invasive insect Cydalima perspectalis modulates the metabolism re-orchestration of native Buxus sempervirens.Plant biology (Stuttgart, Germany) · 2025Article
- Investigation of the reproducibility of the treatment efficacy of a commercial bio stimulant using metabolic profiling on flax.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Non-Targeted Nuclear Magnetic Resonance Analysis for Food Authenticity: A Comparative Study on Tomato Samples.Molecules (Basel, Switzerland) · 2024Article
- NMR and LC-MS-based metabolomics to investigate the efficacy of a commercial bio stimulant for the treatment of wheat (Triticum aestivum).Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Compound-Specific 1DACS omega · 2023Article
- Byproducts of Globe Artichoke and Cauliflower Production as a New Source of Bioactive Compounds in the Green Economy Perspective: An NMR Study.Molecules (Basel, Switzerland) · 2023Article
- Solid-State NMR Investigations of Extracellular Matrixes and Cell Walls of Algae, Bacteria, Fungi, and Plants.Chemical reviews · 2022Review
- NMR, LC-MS Characterization ofMolecules (Basel, Switzerland) · 2022Article
- Article
- Metabolite Fingerprinting UsingMolecules (Basel, Switzerland) · 2021Article
- The exposome paradigm to predict environmental health in terms of systemic homeostasis and resource balance based on NMR data science.RSC advances · 2021Review
- Improved Automated Quantification Algorithm (AQuA) and Its Application to NMR-Based Metabolomics of EDTA-Containing Plasma.Analytical chemistry · 2021Article
- Automatic 1DMetabolites · 2021Review
- NMR and LC-MS-Based Metabolomics to Study Osmotic Stress in Lignan-Deficient Flax.Molecules (Basel, Switzerland) · 2021Article
- The Tomato Guanylate-Binding Protein SlGBP1 Enables Fruit Tissue Differentiation by Maintaining Endopolyploid Cells in a Non-Proliferative State.The Plant cell · 2020Article
- NMR Metabolomics Applied on the Discrimination of Variables Influencing Tomato (Molecules (Basel, Switzerland) · 2020Review
- The Zebra Mussel (Metabolites · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionProton nuclear magnetic resonance spectroscopy (
objectivesThe aim of the present work is to provide advice for minimizing uncontrolled variability in plant sample preparation before and during NMR metabolomic profiling, taking into account sample composition, including its specificity in terms of pH and paramagnetic ion concentrations, and NMR spectrometer performances.
methodsAn automation of spectrometer preparation routine standardization before NMR acquisition campaign was implemented and tested on three plant sample sets (extracts of durum wheat spikelet, Arabidopsis leaf and root, and flax leaf, root and stem). We performed
resultsComparability of large- (Arabidopsis) and medium-size (flax) datasets measured at 600 MHz and from the wheat sample set recorded at the three sites (400, 500 and 600 MHz) was exceptionally good in terms of spectral quality. The coefficient of variation of the full width at half maximum (FWHM) and the signal-to-noise ratio (S/N) of two selected peaks was comprised between 5 and 10% depending on the size of sample set and the spectrometer field. EDTA addition improved citrate and malate resonance patterns for wheat sample sets. A collection of 22 samples of wheat spikelet extracts was used as a proof of concept and showed that the data collected at the three sites on instruments of different field strengths and manufacturers yielded the same discrimination pattern of the biological groups.
conclusionStandardization or automation of several steps from extract preparation to data reduction improves data quality for small to large collections of plant samples of different origins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.