ArticleMetabolomics : Official journal of the Metabolomic Society2017
Article in Metabolomics : Official journal of the Metabolomic Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 102 citations in OpenAlex.
- Coral color morphs exhibit distinct microbial and proteomic profiles linked to stress and immune mechanisms in a changing ocean.Microbiome · 2026Article
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- Global coral genomic vulnerability explains recent reef losses.Nature communications · 2025Article
- Sterols are key to coral larvae survival, swimming capacity, and thermal tolerance.Communications biology · 2025Article
- Physiology and metabolism of eukaryotic microalgae involved in aquatic photosymbioses.The New phytologist · 2025Review
- Inhibiting inositol transport disrupts metabolite profiles and mimics heat stress in a model cnidarian-Symbiodiniaceae symbiosis.Communications biology · 2025Article
- Heat-Evolved Microalgae (Symbiodiniaceae) Are Stable Symbionts and Influence Thermal Tolerance of the Sea Anemone Exaiptasia diaphana.Environmental microbiology · 2025Article
- Coral larvae increase nitrogen assimilation to stabilize algal symbiosis and combat bleaching under increased temperature.PLoS biology · 2024Article
- Paired metabolomics and volatilomics provides insight into transient high light stress response mechanisms of the coral Montipora mollis.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Multiomics data integration, limitations, and prospects to reveal the metabolic activity of the coral holobiont.FEMS microbiology ecology · 2024Review
- Multi-Chemical Omics Analysis of the SymbiodiniaceaeMicroorganisms · 2024Article
- Symbiodiniaceae photophysiology and stress resilience is enhanced by microbial associations.Scientific reports · 2023Article
- Coral endosymbiont growth is enhanced by metabolic interactions with bacteria.Nature communications · 2023Article
- Article
- The coral microbiome: towards an understanding of the molecular mechanisms of coral-microbiota interactions.FEMS microbiology reviews · 2023Article
- Metabolomic signatures of corals thriving across extreme reef habitats reveal strategies of heat stress tolerance.Proceedings. Biological sciences · 2023Article
- Shifts in predator behaviour following climate induced disturbance on coral reefs.Proceedings. Biological sciences · 2022Article
- Intraspecific variation in polar and nonpolar metabolite profiles of a threatened Caribbean coral.Metabolomics : Official journal of the Metabolomic Society · 2021Article
- Bleaching effect in Sarcophyton spp. soft corals-is there a correlation to their diterpene content?Environmental science and pollution research international · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRising seawater temperatures are threatening the persistence of coral reefs; where above critical thresholds, thermal stress results in a breakdown of the coral-dinoflagellate symbiosis and the loss of algal symbionts (coral bleaching). As symbiont-derived organic products typically form a major portion of host energy budgets, this has major implications for the fitness and persistence of symbiotic corals.
objectivesWe aimed to determine change in autotrophic carbon fate within individual compounds and downstream metabolic pathways in a coral symbiosis exposed to varying degrees of thermal stress and bleaching.
methodsWe applied gas chromatography-mass spectrometry coupled to a stable isotope tracer (
resultsThermal stress resulted in partner-specific changes in carbon fate, which progressed with heat stress duration. We detected modifications to carbohydrate and fatty acid metabolism, lipogenesis, and homeostatic responses to thermal, oxidative and osmotic stress. Despite pronounced photodamage, remaining in hospite symbionts continued to produce organic products de novo and translocate to the coral host. However as bleaching progressed, we observed minimal
conclusionThese data have major implications for our understanding of coral symbiosis function during bleaching. Our findings suggest that during early stage bleaching, remaining symbionts continue to effectively translocate a variety of organic products to the host, however under prolonged thermal stress there is likely a reduction in the quality of these products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.