ReviewCurrent genetics2019
Spx, a versatile regulator of the Bacillus subtilis stress response.
Review in Current genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Structure-function analysis of the bacterial ClpE-ClpP AAA+ protease.The Journal of biological chemistry · 2026Article
- Article
- ComK-induced cell death is reversed by upregulating the SigB or Spx pathway inMicrobiology spectrum · 2025Article
- Article
- (p)ppGpp - an important player during heat shock response.microLife · 2023Review
- Cervimycin-Resistant Staphylococcus aureus Strains Display Vancomycin-Intermediate Resistant Phenotypes.Microbiology spectrum · 2022Article
- Gene Silencing through CRISPR Interference in Mycoplasmas.Microorganisms · 2022Article
- Disruption of theJournal of bacteriology · 2022Article
- Update on the Protein Homeostasis Network inFrontiers in microbiology · 2022Review
- Redirected Stress Responses in a Genome-Minimized 'midimSystems · 2021Article
- Regulatory circuits controlling Spx levels in Streptococcus mutans.Molecular microbiology · 2020Article
- Structural basis of non-canonical transcriptional regulation by the σA-bound iron-sulfur protein WhiB1 in M. tuberculosis.Nucleic acids research · 2020Article
- Protein aggregation in bacteria.FEMS microbiology reviews · 2020Review
- ZnO and TiO2 nanoparticles alter the ability of Bacillus subtilis to fight against a stress.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Spx is a central regulator of the Bacillus subtilis stress response. By binding to the alpha subunits of RNA polymerase, it regulates the expression of many stress response genes, while concurrently interfering with various developmental processes. The recent observation that Spx also represses transcription of ribosomal RNA adds a direct link between stress response and the control of translation in B. subtilis. Here, we discuss the significance of the regulation of translation and the transcription of translation-related genes during the bacterial stress response and the role of Spx in this process. Furthermore, we compare Spx with the role of DksA during stress response in proteobacteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.