Evidence map›Paper›PMID 30829819›Full record

ArticleThe Journal of head trauma rehabilitation

Comorbid Conditions Among Adults 50 Years and Older With Traumatic Brain Injury: Examining Associations With Demographics, Healthcare Utilization, Institutionalization, and 1-Year Outcomes.

Raj G Kumar, Jennifer Olsen, Shannon B Juengst, Kristen Dams-OʼConnor, Therese M OʼNeil-Pirozzi, Flora M Hammond, Amy K Wagner

Abstract read
In one paragraph

Article in The Journal of head trauma rehabilitation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Long-term life expectancy in severe traumatic brain injury: a systematic review.European journal of physical and rehabilitation medicine · 2024
    Pooled it
  2. Comorbidity in traumatic brain injury and functional outcomes: a systematic review.European journal of physical and rehabilitation medicine · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raj G KumarDepartments of Physical Medicine & Rehabilitation (Drs Kumar, Olsen, and Wagner) and Epidemiology (Dr Kumar), Clinical and Translational Science Institute, Center for Neuroscience, and Safar Center for Resuscitation Research (Dr Wagner), University of Pittsburgh, Pennsylvania; Departments of Physical Medicine and Rehabilitation (Dr Juengst) and Rehabilitation Counseling (Dr Juengst), UT Southwestern, Dallas, Texas; Department of Rehabilitation and Human Performance and Department of Neurology, Icahn School of Medicine at Mount Sinai, New York (Dr Dams-O'Connor); Department of Communication Sciences and Disorders, Northeastern University, Boston, Massachusetts (Dr O'Neil-Pirozzi); Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, Massachusetts (Dr O'Neil-Pirozzi); and Department of Physical Medicine and Rehabilitation, Indiana University School of Medicine, Indianapolis (Dr Hammond).
Jennifer Olsen
Shannon B Juengst
Kristen Dams-OʼConnor
Therese M OʼNeil-Pirozzi
Flora M Hammond
Amy K Wagner

Funding

NRSA Training CoreTL1TR001858 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RADOMSKI, THOMAS, RUBIO, DORIS M · 2016 to 2025
$11.1M
Comprehensive Investigation of the Clinical Course of Traumatic Brain InjuryK01HD074651 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DAMS-O'CONNOR, KRISTEN · 2014 to 2018
$536k
NCATS NIH HHS TL1 TR001858NCCDPHP CDC HHS U48 DP000039NCCDPHP CDC HHS U48 DP000041NICHD NIH HHS K01 HD074651
6 · The paper itself

Abstract

objectivesTo assess the relationship of acute complications, preexisting chronic diseases, and substance abuse with clinical and functional outcomes among adults 50 years and older with moderate-to-severe traumatic brain injury (TBI).

designProspective cohort study.

participantsAdults 50 years and older with moderate-to-severe TBI (n = 2134). MEASURES: Clusters of comorbid health conditions empirically derived from non-injury International Classification of Diseases, Ninth Revision codes, demographic/injury variables, and outcome (acute and rehabilitation length of stay [LOS], Functional Independence Measure efficiency, posttraumatic amnesia [PTA] duration, institutionalization, rehospitalization, and Glasgow Outcome Scale-Extended (GOS-E) at 1 year).

resultsIndividuals with greater acute hospital complication burden were more often middle-aged men, injured in motor vehicle accidents, and had longer LOS and PTA. These same individuals experienced higher rates of 1-year rehospitalization and greater odds of unfavorable GOS-E scores at 1 year. Those with greater chronic disease burden were more likely to be rehospitalized at 1 year. Individuals with more substance abuse burden were most often younger (eg, middle adulthood), black race, less educated, injured via motor vehicle accidents, and had an increased risk for institutionalization.

conclusionPreexisting health conditions and acute complications contribute to TBI outcomes. This work provides a foundation to explore effects of comorbidity prevention and management on TBI recovery in older adults.

Indexed as

AgedAged, 80 and overBrain Injuries, TraumaticChronic DiseaseCombined Modality TherapyComorbidityCorrelation of DataDemographyFemaleGlasgow Outcome ScaleHumansIndependent LivingInstitutionalizationMaleMiddle AgedPatient Acceptance of Health Care

Identifiers

PMID30829819
PMCPMC10234605

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.