SynthesisForensic science, medicine, and pathology2019
Modeling of inflicted head injury by shaking trauma in children: what can we learn? : Part I: A systematic review of animal models.
Synthesis in Forensic science, medicine, and pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Modeling of inflicted head injury by shaking trauma in children: what can we learn? : Update to parts I&II: A systematic review of animal, mathematical and physical models.Forensic science, medicine, and pathology · 2025Pooled it
- Modeling of inflicted head injury by shaking trauma in children: what can we learn? : Part II: A systematic review of mathematical and physical models.Forensic science, medicine, and pathology · 2019Pooled it
- Reassessment of two finite-element studies of infant head trauma: limits of the modelling evidence for shaking-induced bridging-vein rupture and protection by enlarged subarachnoid spaces.Frontiers in bioengineering and biotechnology · 2026Article
- Comparing the kinematics related to inflicted head injury between violent shaking of a 6-week-old and a 1-year-old infant surrogate.Royal Society open science · 2025Article
- Cyclosporine A Accelerates Neurorecovery Transcriptional Trajectory in a Swine Model of Diffuse Traumatic Brain Injury.International journal of molecular sciences · 2025Article
- Abusive Head Trauma Animal Models: Focus on Biomarkers.International journal of molecular sciences · 2023Review
- Animal models of pediatric abusive head trauma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Review
- Parenchymal brain injuries in abusive head trauma.Pediatric radiology · 2021Review
- Violent Infant Surrogate Shaking: Continuous High-Magnitude Centripetal Force and Abrupt Shift in Tangential Acceleration May Explain High Risk of Subdural Hemorrhage.Neurotrauma reports · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflicted blunt force trauma and/or repetitive acceleration-deceleration trauma in infants can cause brain injury. Yet, the exact pathophysiologic mechanism with its associated thresholds remains unclear. In this systematic review an overview of animal models for shaking trauma and their findings on tissue damage will be provided. A systematic review was performed in MEDLINE and Scopus for articles on the simulation of inflicted head injury in animals. After collection, the studies were independently screened by two researchers for title, abstract, and finally full text and on methodological quality. A total of 12 articles were included after full-text screening. Three articles were based on a single study population of 13 lambs, by one research group. The other 9 articles were separate studies in piglets, all by a single second research group. The lamb articles give some information on tissue damage after inflicted head injury. The piglet studies only provide information on consequences of a single plane rotational movement. Generally, with increasing age and weight, there was a decrease of axonal injury and death. Future studies should focus on every single step in the process of a free movement in all directions, resembling human infant shaking. In part II of this systematic review biomechanical models will be evaluated.
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