Evidence map›Paper›PMID 30828648›Full record

ArticleNano futures2018

Sensing the electrical activity of single ion channels with top-down silicon nanoribbons.

Weiwei Zhou, Luye Mu, Jinfeng Li, Mark Reed, Peter J Burke

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nano futures, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Weiwei ZhouDepartment of Electrical Engineering and Computer Science, University of California, Irvine, CA, United States of America.
Luye MuDepartment of Electrical Engineering; Department of Applied Physics, Yale University, New Haven, CT, United States of America.
Jinfeng LiDepartment of Electrical Engineering and Computer Science, University of California, Irvine, CA, United States of America.
Mark ReedDepartment of Electrical Engineering; Department of Applied Physics, Yale University, New Haven, CT, United States of America.
Peter J BurkeDepartment of Electrical Engineering and Computer Science, University of California, Irvine, CA, United States of America.ORCID 0000-0002-8883-1014

Funding

High-throughput on-chip platform for interrogation of mitochondrial membrane potential and apoptosisR33CA182384 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI BURKE, PETER J. · 2015 to 2017
$1.2M
Nanoelectrode arrays for study of the molecular mechanisms, triggers, and inhibitR21CA143351 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI BURKE, PETER J. · 2010 to 2012
$631k
NCI NIH HHS R21 CA143351NCI NIH HHS R33 CA182384
6 · The paper itself

Abstract

Using top-down fabricated silicon nanoribbons, we measure the opening and closing of ion channels alamethicin and gramicidin A. A capacitive model of the system is proposed to demonstrate that the geometric capacitance of the nanoribbon is charged by ion channel currents. The integration of top-down nanoribbons with electrophysiology holds promise for integration of electrically active living systems with artificial electronics.

Indexed as

electrophysiologyion channelnanowire

Identifiers

PMID30828648
PMCPMC6390970

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.