Evidence map›Paper›PMID 30828634›Full record

ReviewLaryngoscope investigative otolaryngology2019

Cellular and molecular mechanisms of cleft palate development.

Anita S Deshpande, Steven L Goudy

Abstract readReview
In one paragraph

Review in Laryngoscope investigative otolaryngology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Review
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  6. Review
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  11. Review
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  13. Single cell sequencing of the mouse anterior palate reveals mesenchymal heterogeneity.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  14. Article
  15. Article
  16. Article
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  18. Article
  19. A Novel Van der Woude Syndrome-CausingFrontiers in cell and developmental biology · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anita S DeshpandeFrom the Department of Otolaryngology-Head and Neck Surgery Emory University School of Medicine Atlanta Georgia U.S.A.ORCID https://orcid.org/0000-0001-6920-2864
Steven L GoudyFrom the Department of Otolaryngology-Head and Neck Surgery Emory University School of Medicine Atlanta Georgia U.S.A.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cleft lip and palate are common craniofacial deformities. The etiology underlying these deformities is complex and multifactorial and they can occur as part of one of many chromosomal syndromes, Mendelian single gene disorders, teratogenic effects, and as yet uncharacterized syndromes. Our paper will provide an overview of the multiple genes and molecular pathways that have been implicated in palatal fusion. We believe that understanding the molecular mechanisms of cleft formation can help clinicians anticipate which patients may have difficulties healing and in the future allow them to make surgical and medical treatment decisions based on genetic information.

Indexed as

Cleft lipcleft palateembryologygeneticsmolecular pathways

Identifiers

PMID30828634
PMCPMC6383315

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.