Evidence map›Paper›PMID 30828434›Full record

ReviewF1000Research2019

Recent advances in understanding biliary atresia.

Andrew Wehrman, Orith Waisbourd-Zinman, Rebecca G Wells

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  8. Article
  9. Article
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  11. Article
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  13. Article
  14. Review
  15. Review
  16. Review
  17. In Utero Extrahepatic Bile Duct Damage and Repair: Implications for Biliary Atresia.Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Andrew WehrmanGastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.ORCID 0000-0002-2293-4037
Orith Waisbourd-ZinmanGastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
Rebecca G WellsMedicine and Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · US

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Rebecca A Simmons · 2006 to 2026
$35.3M
Injury, Progression, and Fibrosis of the Extrahepatic Bile DuctR01DK119290 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI REBECCA G WELLS · 2019 to 2026
$2.9M
Training Program in the Genetic Basis of Pediatric Gastrointestinal DisordersT32DK101371 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI ROBERT O HEUCKEROTH, Judith Rachel Kelsen · 2014 to 2026
$2.5M
Injury, progression, and fibrosis of the extrahepatic bile ductR56DK119290 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI WELLS, REBECCA G · 2018 to 2018
$403k
NIDDK NIH HHS R01 DK119290NIDDK NIH HHS R56 DK119290NIDDK NIH HHS T32 DK101371NIEHS NIH HHS P30 ES013508
6 · The paper itself

Abstract

Biliary atresia (BA) is a neonatal liver disease characterized by progressive obstruction and fibrosis of the extrahepatic biliary tree as well as fibrosis and inflammation of the liver parenchyma. Recent studies found that infants who will go on to develop BA have elevated direct bilirubin levels in the first few days of life, suggesting that the disease starts

Indexed as

Biliary AtresiaHumansInfantInflammationLiver Cirrhosisbile ductbilirubinhepatoportoenterostomyKasai

Identifiers

PMID30828434
PMCPMC6392153
OpenAlexW2917608643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.