Evidence map›Paper›PMID 30828133›Full record

ArticleSensors and actuators. B, Chemical2019

Point-of-care Colorimetric Analysis through Smartphone Video.

Benjamin Coleman, Chad Coarsey, Md Alamgir Kabir, Waseem Asghar

Abstract read
In one paragraph

Article in Sensors and actuators. B, Chemical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  8. Diagnosis for COVID-19: current status and future prospects.Expert review of molecular diagnostics · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Benjamin ColemanAsghar-Lab, Micro and Nanotechnology for Medicine, College of Engineering and Computer Science, Boca Raton, FL 33431.
Chad CoarseyAsghar-Lab, Micro and Nanotechnology for Medicine, College of Engineering and Computer Science, Boca Raton, FL 33431.
Md Alamgir KabirAsghar-Lab, Micro and Nanotechnology for Medicine, College of Engineering and Computer Science, Boca Raton, FL 33431.
Waseem AsgharAsghar-Lab, Micro and Nanotechnology for Medicine, College of Engineering and Computer Science, Boca Raton, FL 33431.

Funding

Development of disposable and refrigeration-free microchip technology for CD4+ T cell counting at point-of-care settingsR15AI127214 · NIAID · FLORIDA ATLANTIC UNIVERSITY · PI ASGHAR, WASEEM · 2016 to 2016
$460k
NIAID NIH HHS R15 AI127214
6 · The paper itself

Abstract

Point-of-care (POC) tests often rely on smartphone image methods for colorimetric analysis, but the results of such methods are frequently difficult to reproduce or standardize. The problem is aggravated by unpredictable image capture conditions, which pose a significant challenge when low limits of detection (LOD) are needed. Application-specific smartphone attachments are often used to standardize imaging conditions, but there has recently been an interest in equipment-free POC colorimetric analysis. Improved output metrics and preprocessing methods have been developed, but equipment-free imaging often has a high LOD and is inappropriate for quantitative tasks. Additional work is necessary to replace external smartphone attachments with algorithms. Towards this end, we have developed a video processing method that synthesizes many images into a single output metric. We use image features to select the best inputs from a large set of video frames and demonstrate that the resulting output values have a stronger correlation with laboratory methods and a lower standard error. The developed algorithm only requires 20 seconds of video and can easily be integrated with existing processing methods. We apply our algorithm to the NS1-based sandwich ELISA for Zika detection and show that the LOD is two times lower when our video-based method is used.

Indexed as

BiosensorCell phonePoint of careSmartphoneZika Detection

Identifiers

PMID30828133
PMCPMC6391882

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.