Evidence map›Paper›PMID 30828115›Full record

ReviewThe Clinical biochemist. Reviews2018

Lead Toxicity: an Australian Perspective.

Gemma M Daley, Carel J Pretorius, Jacobus Pj Ungerer

Open access · greenAbstract readReview
PubMed Full text at PMC
In one paragraph

Review in The Clinical biochemist. Reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gemma M DaleyDepartment of Chemical Pathology, Pathology Queensland Central Laboratory, University of Queensland, Brisbane, Qld 4006, Australia.
Carel J PretoriusDepartment of Chemical Pathology, Pathology Queensland Central Laboratory, University of Queensland, Brisbane, Qld 4006, Australia.
Jacobus Pj UngererDepartment of Chemical Pathology, Pathology Queensland Central Laboratory, University of Queensland, Brisbane, Qld 4006, Australia.
The University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plumbism refers to the clinical features of lead toxicity, a condition which has been identified and then forgotten in a depressingly cyclical fashion since ancient times. For the past 6000 years antiquarians have described the human use of lead despite the well documented and severe adverse effects of exposure. As the analytical methods of lead measurement bring improved detection capability, it is clear that there is no safe amount of lead in the body. Sadly, we continue to identify affected patients in contemporary Australia, including young children. While there is little evidence that chelation therapy improves outcomes in affected individuals, it is recommended for use in patients with acute encephalopathy or in those with particularly elevated levels. The paucity of evidence supporting active treatment of plumbism highlights the importance of primary prevention, particularly in our most vulnerable.

Identifiers

PMID30828115
PMCPMC6372192
OpenAlexW2924990955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.