ArticleCurrent biology : CB2019
Ad libitum Weekend Recovery Sleep Fails to Prevent Metabolic Dysregulation during a Repeating Pattern of Insufficient Sleep and Weekend Recovery Sleep.
Article in Current biology : CB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
111 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- From factory floors to dream doors: a systematic review of sleep interventions in industrial workers.BMC public health · 2026Pooled it
- The Association Between Sleep Duration and the Risk of Hypertension: A Systematic Review and Meta-analysis of Cohort Studies.Journal of general internal medicine · 2025Pooled it
- Sleep Extension Improves Sleep Health but Not Insulin Sensitivity in People With Overweight or Obesity Who Maintain Habitual Short Sleep Schedules.Diabetes care · 2026Trial
- Trial
- Early time-restricted eating advances sleep in late sleepers: a pilot randomized controlled trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Trial
- Insufficient sleep and weekend recovery sleep: classification by a metabolomics-based machine learning ensemble.Scientific reports · 2023Trial
- Effects of ad libitum food intake, insufficient sleep and weekend recovery sleep on energy balance.Sleep · 2021Trial
- Trial
- Mild sleep restriction increases 24-hour ambulatory blood pressure in premenopausal women with no indication of mediation by psychological effects.American heart journal · 2020Trial
- Ramadan Fasting in Metabolic Dysfunction-Associated Steatotic Liver Disease: Linking the Gut-Mitophagy-Circadian Axis to Endothelial Dysfunction and Hepatic Outcomes.Journal of personalized medicine · 2026Review
- Acute sleep rebound following sleep restriction is associated with reduced mortality risk.Nature communications · 2026Article
- Glucose homeostasis during recurrent periods of sleep restriction and recovery in healthy young adults.Sleep · 2026Article
- Time-Restricted Eating, Cardiometabolic Health in Obesity and The Optimal Length of the Eating Window.Current nutrition reports · 2026Review
- Association of weekday sleep duration and estimated glucose disposal rate: the role of weekend catch-up sleep.BMJ open diabetes research & care · 2026Article
- Examining the Role of Sleep in Body Weight Regulation and Implications for Obesity Treatment: A Narrative Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Association Between Workday Sleep Deprivation, Weekend Catch-Up Sleep, and Abdominal Adiposity Indicators: A Cross-Sectional Study Among Brazilian Female Fixed-Shift Workers.Diseases (Basel, Switzerland) · 2026Article
- A Dynamic Model of Weekly Sleep Timing: Endogenous Origins of Social Jetlag.Nature and science of sleep · 2026Article
- Objectively measured sleep regularity, weekend recovery sleep, and the risk of incident type 2 diabetes: a prospective cohort study from the UK Biobank.International journal of surgery (London, England) · 2026Article
- From yawn to dawn: the effects of a sleep extension intervention on objective and subjective dimensions of sleep health in adults with habitual short sleep duration.Sleep advances : a journal of the Sleep Research Society · 2026Article
- How Does the Sleep Regularity Questionnaire Relate to Wearable- and Diary-Derived Sleep Regularity?Journal of circadian rhythms · 2026Article
51 more citing papers are in PubMed but not listed here.
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11 authors.
Funding
Abstract
People commonly increase sleep duration on the weekend to recover from sleep loss incurred during the workweek. Whether ad libitum weekend recovery sleep prevents metabolic dysregulation caused by recurrent insufficient sleep is unknown. Here, we assessed sleep, circadian timing, energy intake, weight gain, and insulin sensitivity during sustained insufficient sleep (9 nights) and during recurrent insufficient sleep following ad libitum weekend recovery sleep. Healthy, young adults were randomly assigned to one of three groups: (1) control (CON; 9-h sleep opportunities, n = 8), (2) sleep restriction without weekend recovery sleep (SR; 5-h sleep opportunities, n = 14), and (3) sleep restriction with weekend recovery sleep (WR; insufficient sleep for 5-day workweek, then 2 days of weekend recovery, then 2 nights of insufficient sleep, n = 14). For SR and WR groups, insufficient sleep increased after-dinner energy intake and body weight versus baseline. During ad libitum weekend recovery sleep, participants cumulatively slept ∼1.1 h more than baseline, and after-dinner energy intake decreased versus insufficient sleep. However, during recurrent insufficient sleep following the weekend, the circadian phase was delayed, and after-dinner energy intake and body weight increased versus baseline. In SR, whole-body insulin sensitivity decreased ∼13% during insufficient sleep versus baseline, and in WR, whole-body, hepatic, and muscle insulin sensitivity decreased ∼9%-27% during recurrent insufficient sleep versus baseline. Furthermore, during the weekend, total sleep duration was lower in women versus men, and energy intake decreased to baseline levels in women but not in men. Our findings suggest that weekend recovery sleep is not an effective strategy to prevent metabolic dysregulation associated with recurrent insufficient sleep.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.