Evidence map›Paper›PMID 30827415›Full record

ArticleCellular and molecular gastroenterology and hepatology2019

Gastroesophageal Reflux Induces Protein Adducts in the Esophagus.

Ravindran Caspa Gokulan, Jamie M Adcock, Irene Zagol-Ikapitte, Raymond Mernaugh, Phillip Williams, Kay M Washington, Olivier Boutaud, John A Oates, Sergey I Dikalov, Alexander I Zaika

Abstract readLetter
In one paragraph

Article in Cellular and molecular gastroenterology and hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Oxidative modification of HDL by lipid aldehydes impacts HDL function.Archives of biochemistry and biophysics · 2022
    Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ravindran Caspa GokulanDepartment of Surgery, University of Miami, Miami, Florida.
Jamie M AdcockDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Irene Zagol-IkapitteDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Raymond MernaughDepartment of Biochemistry, Vanderbilt University, Nashville, Tennessee.
Phillip WilliamsDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Kay M WashingtonDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee.
Olivier BoutaudDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee.
John A OatesDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee.
Sergey I DikalovDivision of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee.
Alexander I ZaikaDepartment of Surgery, University of Miami, Miami, Florida; Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Veterans Affairs, Miami VA Healthcare System, Miami, Florida. Electronic address: axz353@med.miami.edu.

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal CancerP50CA236733 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Robert J. Coffey · 2019 to 2026
$19.6M
Regulation of the Oncogenic Stress Response in Helicobacter pylori-infected cellsR01CA138833 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALEXANDER I. ZAIKA · 2010 to 2026
$4.3M
Mechanisms of Tumorigenic Transformation of Barretts EsophagusR01CA206564 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZAIKA, ALEXANDER I. · 2015 to 2019
$1.8M
Sirtuin 3 Impairment and SOD2 Acetylation in Oxidative Stress and HypertensionR01HL124116 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DIKALOV, SERGEY · 2015 to 2018
$1.6M
LSM880-Airyscan Confocal Microscope for Large Shared ResourceS10OD021630 · OD · VANDERBILT UNIVERSITY · PI WELLS, K. SAM · 2016 to 2016
$560k
Prevention of COX-2 Derived DNA and Histone Modifications in CancerR21CA187495 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OATES, JOHN ALEXANDER · 2015 to 2016
$394k
Prevention of genomic instability by a scavenger of bifunctional electrophilesR21CA201856 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OATES, JOHN ALEXANDER · 2016 to 2017
$384k
Regulation of gastroesophageal reflux-associated tumorigenesisI01BX002115 · VA · VETERANS HEALTH ADMINISTRATION · PI ZAIKA, ALEXANDER I. · 2014 to 2024
–
BLRD VA I01 BX002115NCI NIH HHS P50 CA236733NCI NIH HHS R01 CA138833NCI NIH HHS R01 CA206564NCI NIH HHS R21 CA187495NCI NIH HHS R21 CA201856NHLBI NIH HHS R01 HL124116NIDDK NIH HHS P30 DK058404NIH HHS S10 OD021630
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcetylcysteineAnimalsBenzylaminesBile Acids and SaltsCell LineCyclic N-OxidesEsophagusGastroesophageal RefluxHumansLipidsMiceSpin LabelsTumor Suppressor Protein p532-(aminomethyl)phenolAcetylcysteineBenzylaminesBile Acids and SaltsCyclic N-OxidesisolevuglandinLipidsSpin LabelstempolTumor Suppressor Protein p53

Identifiers

PMID30827415
PMCPMC6410348

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.