Evidence map›Paper›PMID 30827288›Full record

ArticlePublic health nutrition2019

Elevated highly sensitive C-reactive protein and d-dimer levels are associated with food insecurity among people living with HIV in Pune, India.

Sandesh Patil, Dileep Kadam, Nicky Mehtani, Shashikala Sangle, Ivan Marbaniang, Vandana Kulkarni, Dhananjay Shere, Prasad Deshpande, Gauri Dhumal, Nishi Suryavanshi and 9 more

Abstract read
In one paragraph

Article in Public health nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Sandesh Patil1Byramjee Jeejeebhoy Government Medical College - Johns Hopkins University Clinical Research Site,1st Floor,Pathology Museum,J P Narayan Road,Pune 411 001,India.
Dileep Kadam2Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals,Pune,India.
Nicky Mehtani3Johns Hopkins School of Medicine,Baltimore,MD,USA.
Shashikala Sangle2Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals,Pune,India.
Ivan Marbaniang1Byramjee Jeejeebhoy Government Medical College - Johns Hopkins University Clinical Research Site,1st Floor,Pathology Museum,J P Narayan Road,Pune 411 001,India.
Vandana Kulkarni1Byramjee Jeejeebhoy Government Medical College - Johns Hopkins University Clinical Research Site,1st Floor,Pathology Museum,J P Narayan Road,Pune 411 001,India.
Dhananjay Shere1Byramjee Jeejeebhoy Government Medical College - Johns Hopkins University Clinical Research Site,1st Floor,Pathology Museum,J P Narayan Road,Pune 411 001,India.
Prasad Deshpande1Byramjee Jeejeebhoy Government Medical College - Johns Hopkins University Clinical Research Site,1st Floor,Pathology Museum,J P Narayan Road,Pune 411 001,India.
Gauri Dhumal1Byramjee Jeejeebhoy Government Medical College - Johns Hopkins University Clinical Research Site,1st Floor,Pathology Museum,J P Narayan Road,Pune 411 001,India.
Nishi Suryavanshi1Byramjee Jeejeebhoy Government Medical College - Johns Hopkins University Clinical Research Site,1st Floor,Pathology Museum,J P Narayan Road,Pune 411 001,India.
Nikhil Gupte1Byramjee Jeejeebhoy Government Medical College - Johns Hopkins University Clinical Research Site,1st Floor,Pathology Museum,J P Narayan Road,Pune 411 001,India.
Robert Bollinger3Johns Hopkins School of Medicine,Baltimore,MD,USA.
Andrea DeLuca3Johns Hopkins School of Medicine,Baltimore,MD,USA.
Neetal Nevrekar1Byramjee Jeejeebhoy Government Medical College - Johns Hopkins University Clinical Research Site,1st Floor,Pathology Museum,J P Narayan Road,Pune 411 001,India.
Pramila Menon4Department of Genetics,Immunology, Biotechnology and Nutrition,Maharashtra University of Health Sciences,Regional Centre,Pune,India.
Rama Kawade4Department of Genetics,Immunology, Biotechnology and Nutrition,Maharashtra University of Health Sciences,Regional Centre,Pune,India.
Mansi Patil4Department of Genetics,Immunology, Biotechnology and Nutrition,Maharashtra University of Health Sciences,Regional Centre,Pune,India.
Amita Gupta3Johns Hopkins School of Medicine,Baltimore,MD,USA.
Vidya Mave1Byramjee Jeejeebhoy Government Medical College - Johns Hopkins University Clinical Research Site,1st Floor,Pathology Museum,J P Narayan Road,Pune 411 001,India.

Funding

The Asia-Pacific HIV Research CollaborationU01AI069907 · NIAID · FOUNDATION FOR AIDS RESEARCH · PI ANNETTE H SOHN · 2006 to 2026
$44.8M
The Johns Hopkins Baltimore-Washington-India Clinical Trials Unit (BWI CTU)UM1AI069465 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Charles W. Flexner, Amita Gupta · 2012 to 2026
$34.1M
HIV-TB Fogarty Research Training ProgramD43TW009574 · FIC · JOHNS HOPKINS UNIVERSITY · PI BOLLINGER, ROBERT C. · 2013 to 2017
$1.0M
FIC NIH HHS D43 TW009574NIAID NIH HHS U01 AI069907NIAID NIH HHS UM1 AI069465
6 · The paper itself

Abstract

objectiveTo assess the prevalence and determinants of food insecurity among people living with HIV (PLWH) in Pune, India and its association with biomarkers known to confer increased risks of morbidity and mortality in this population.

designCross-sectional analysis assessing food insecurity using the standardized Household Food Insecurity Access Scale. Participants were dichotomized into two groups: food insecure and food secure. Logistic regression models were used to assess associations between socio-economic, demographic, clinical, biochemical factors and food insecurity.

settingAntiretroviral therapy (ART) centre of Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals (BJGMC-SGH), Pune, a large publicly funded tertiary and teaching hospital in western India.ParticpantsAdult (≥18 years) PLWH attending the ART centre between September 2015 and May 2016 who had received ART for either ≤7d (ART-naïve) or ≥1 year (ART-experienced).

resultsFood insecurity was reported by 40 % of 483 participants. Independent risk factors (adjusted OR; 95 % CI) included monthly family income <INR 5000 (~70 USD; 13·2; CI 5·4, 32·2) and consuming ≥4 non-vegetarian meals per week (4·7; 1·9, 11·9). High-sensitivity C-reactive protein (hs-CRP) ≥0·33 mg/dl (1·6; 1·04, 2·6) and d-dimer levels 0·19-0·31 µg/ml (1·6; 1·01, 2·6) and ≥0·32 µg/ml (1·9; 1·2, 3·2) were also associated with food insecurity.

conclusionsMore than a third of the study participants were food insecure. Furthermore, higher hs-CRP and d-dimer levels were associated with food insecurity. Prospective studies are required to understand the relationship between food insecurity, hs-CRP and d-dimer better.

Indexed as

HIV InfectionsAdultC-Reactive ProteinCross-Sectional StudiesFemaleFibrin Fibrinogen Degradation ProductsFood SupplyHumansIndiaMaleMiddle AgedYoung AdultC-Reactive ProteinFibrin Fibrinogen Degradation Productsfibrin fragment Dd-DimerFood insecurityHigh-sensitivity C-reactive proteinHIVIndia

Identifiers

PMID30827288
PMCPMC6561786

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.