Evidence map›Paper›PMID 30827204›Full record

ArticleThyroid : official journal of the American Thyroid Association2019

Iodine Nutrition in Weaning Infants in the United States.

Roja Fallah, Lin Du, Lewis E Braverman, Xuemei He, Miriam Segura-Harrison, Michael W Yeh, Elizabeth N Pearce, Harvey K Chiu, Steven D Mittelman, Angela M Leung

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. An endocrinologist's journey in iodine nutrition.European journal of clinical nutrition · 2022
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Roja Fallah1 Division of Pediatric Endocrinology, Department of Pediatrics; UCLA David Geffen School of Medicine, Los Angeles, California.
Lin Du2 Department of Biostatistics, UCLA Fielding School of Public Health, Los Angeles, California.
Lewis E Braverman3 Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, Massachusetts.
Xuemei He3 Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, Massachusetts.
Miriam Segura-Harrison4 Department of Family Medicine, Memorial Hospital of Rhode Island, Brown University, Pawtucket, Rhode Island.
Michael W Yeh5 Section of Endocrine Surgery, Department of Surgery; UCLA David Geffen School of Medicine, Los Angeles, California.
Elizabeth N Pearce6 Division of Endocrinology, Diabetes, and Metabolism; UCLA David Geffen School of Medicine, Los Angeles, California.
Harvey K Chiu1 Division of Pediatric Endocrinology, Department of Pediatrics; UCLA David Geffen School of Medicine, Los Angeles, California.
Steven D Mittelman1 Division of Pediatric Endocrinology, Department of Pediatrics; UCLA David Geffen School of Medicine, Los Angeles, California.
Angela M Leung6 Division of Endocrinology, Diabetes, and Metabolism; UCLA David Geffen School of Medicine, Los Angeles, California.
University of California, Los Angeles · USBoston University · USMemorial Hospital of Rhode Island · USUCLA Health · US

Funding

Iodine Nutrition and Thyroid Disease During Pregnancy and LactationK23HD068552 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEUNG, ANGELA MEI-TIN · 2011 to 2015
$644k
NICHD NIH HHS K23 HD068552
6 · The paper itself

Abstract

backgroundAs iodine is a requisite micronutrient for infant brain development, infants are at risk for iodine deficiency during the weaning period when their diet transitions from milk (breast-milk, infant formula, or follow-on formula) to solid food. Dietary iodine intake during this weaning period is likely minimal, as the iodine content of commercial baby food is not regulated, and the addition of salt to baby food is not recommended. This study reports the current status of iodine nutrition among weaning infants in the United States.

methodsSubjects (n = 60; 50% Caucasian, 30% black) were infants <12 months of age who were fed any combination of formula and/or baby food. Samples of all formula and food consumed in the previous 24 hours and a spot urine sample from each infant were obtained for the measurement of iodine. The estimated quantities of ingested formula and baby food were summed from a food diary recorded by the infants' parents.

resultsThe mean age of the infants was 6.3 ± 3.5 months. The median urinary iodine concentration (UIC) was 117 μg/L (range 26.9-1302.8 μg/L). Estimated daily iodine intake obtained from the measured iodine content in infant formula/foods was 89 μg (range 0-288 μg). There was a positive correlation between the infants' UIC and the iodine content in the consumed foods (r = 0.4, p < 0.001).

conclusionsAlthough the median UIC of infants fed a combination of infant formula and baby food would meet the criteria for iodine sufficiency in a larger sample, those consuming the lowest quartile of iodine-containing nutritional sources had a median UIC <100 μg/L.

Indexed as

Bottle FeedingInfant Nutritional Physiological PhenomenaNutritional StatusNutritive ValueRecommended Dietary AllowancesAdultAge FactorsBostonBrainChild DevelopmentFemaleHumansInfantInfant FoodInfant FormulaIodineIodinebrain developmentinfantsiodineiodine nutritionnutrition

Identifiers

PMID30827204
PMCPMC6457884
OpenAlexW2919263209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.