Evidence map›Paper›PMID 30826893›Full record

ReviewCurrent psychiatry reports2019

Treating Circadian Rhythm Disruption in Bipolar Disorder.

Alexandra K Gold, Gustavo Kinrys

Abstract readReview
In one paragraph

Review in Current psychiatry reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Efficacy and Safety of Light Therapy as a Home Treatment for Motor and Non-Motor Symptoms of Parkinson Disease: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. The crosstalk between CREB and PER2 mediates the transition between mania- and depression-like behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  8. Review
  9. Moving toward precision and personalized treatment strategies in psychiatry.The international journal of neuropsychopharmacology · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Bipolar Disorder, Circadian Rhythm and Clock Genes.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Review
  14. Review
  15. Article
  16. Review
  17. Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alexandra K GoldDepartment of Psychological and Brain Sciences, Boston University, 900 Commonwealth Avenue, Boston, MA, 02215, USA. akgold@bu.edu.
Gustavo KinrysMassachusetts General Hospital, Boston, MA, USA.

Funding

Comparative Effectiveness Study for Bipolar DisorderR01HS019371 · AHRQ · MASSACHUSETTS GENERAL HOSPITAL · PI NIERENBERG, ANDREW A · 2010 to 2010
$9.8M
Impaired Risk Avoidance in Bipolar Disorder and Substance Use DisordersF31MH116557 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI GOLD, ALEXANDRA KATE · 2018 to 2021
$100k
AHRQ HHS R01 HS019371NIMH NIH HHS F31 MH116557
6 · The paper itself

Abstract

purpose of reviewDisruptions in circadian rhythms are believed to underlie the illness course of bipolar disorder (BD). This review evaluates recent studies on the treatment of circadian dysfunction in BD. RECENT

findingsTargeted social rhythm therapy may be useful for bipolar depression though some studies suggest that a non-targeted psychosocial or pharmacological intervention may be just as efficacious. Lithium holds potential for addressing circadian dysfunction in BD. Blue-blocking therapy may be useful for mania and midday bright light therapy may relieve depression.

conclusionsPsychosocial, pharmacological, and light-based approaches are promising avenues for treating circadian dysfunction in BD.

Indexed as

Bipolar DisorderCircadian RhythmDepressionDepressive DisorderHumansLithium CompoundsPhototherapyLithium CompoundsBipolar disorderCircadian rhythmsLight therapySocial rhythm therapy

Identifiers

PMID30826893
PMCPMC6812517

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.