ReviewCurrent psychiatry reports2019
The Relationship Between Perinatal Mental Health and Stress: a Review of the Microbiome.
Review in Current psychiatry reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Maternal Prenatal Stress and the Offspring Gut Microbiome: A Cross-Species Systematic Review.Developmental psychobiology · 2025Pooled it
- Feasibility Study ofNutrients · 2023Trial
- Depression as a Cardiovascular Risk Marker in Pregnancy: Hypertensive and Arrhythmic Maternal Outcomes in a Retrospective Matched Cohort.Journal of clinical medicine · 2026Article
- Incidence and risk factors for postnatal mental health-related hospitalisation among Aboriginal and non-Aboriginal women giving birth in the Northern Territory.BMC pregnancy and childbirth · 2026Article
- Postnatal Intrusive Thoughts and Psychotic-Like Experiences: Exploring Associations with Parenting Experiences and Mental Health.Community mental health journal · 2026Article
- The role of music in perinatal mental health, with a psychoneuroimmunological perspective.Brain, behavior, & immunity - health · 2025Article
- Unraveling the role of the gut microbiome in pregnancy disorders: insights and implications.Frontiers in cellular and infection microbiology · 2025Review
- The impact of perinatal maternal stress on the maternal and infant gut and human milk microbiomes: A scoping review.PloS one · 2025Article
- Depressive symptoms and heart rate variability in perinatal women: A narrative review.Japan journal of nursing science : JJNS · 2025Review
- Adverse Childhood Experiences and Perinatal Mental Health: A Review of Progress and Future Directions.Current psychiatry reports · 2024Review
- Maternal Stress Mediates Association of Infant Socioemotional Development with Perinatal Mental Health in Socioeconomically Vulnerable Peruvian Settings.International journal of environmental research and public health · 2024Article
- The impact of perinatal maternal stress on the maternal and infant gut and human milk microbiomes: A scoping review protocol.PloS one · 2024Article
- Prenatal physical activity and the gut microbiota of pregnant women: results from a preliminary investigation.Physical activity and nutrition · 2023Article
- Joint effects of recent stressful life events and adverse childhood experiences on perinatal comorbid anxiety and depression.BMC pregnancy and childbirth · 2023Article
- The risk for nonpsychotic postpartum mood and anxiety disorders during the COVID-19 pandemic.International journal of psychiatry in medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewOur current understanding of the underlying mechanisms and etiologies of perinatal mood and anxiety disorders (PMADs) is not clearly identified. The relationship of stress-induced adaptations (i.e., the hypothalamic-pituitary-adrenal (HPA) axis, the autonomic nervous system (ANS), the immune system) and the microbiota are potential contributors to psychopathology exhibited in women during pregnancy and postpartum and should be investigated. RECENT
findingsThe stress response activates the HPA axis and dysregulates the ANS, leading to the inhibition of the parasympathetic system. Sustained high levels of cortisol, reduced heart variability, and modulated immune responses increase the vulnerability to PMAD. Bidirectional communication between the nervous system and the microbiota is an important factor to alter host homeostasis and development of PMAD. Future research in the relationship between the psychoneuroimmune system, the gut microbiota, and PMAD has the potential to be integrated in clinical practice to improve screening, diagnosis, and treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.