Evidence map›Paper›PMID 30826853›Full record

ArticleSkeletal radiology2019

Needle tenotomy with PRP versus lidocaine in epicondylopathy: clinical and ultrasonographic outcomes over twenty months.

Jose Ignacio Martin, Leire Atilano, Paola Bully, Gotzon Iglesias, Josu Merino, Gonzalo Grandes, Isabel Andia

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Skeletal radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jose Ignacio MartinInterventional Sonography, Department of Radiology, Cruces University Hospital, Barakaldo, Spain.
Leire AtilanoInterventional Sonography, Department of Radiology, Cruces University Hospital, Barakaldo, Spain.
Paola BullyPrimary Care Research Unit of Bizkaia, BioCruces Health Research Institute, Bilbao, Spain.
Gotzon IglesiasInterventional Sonography, Department of Radiology, Cruces University Hospital, Barakaldo, Spain.
Josu MerinoRegenerative Medicine, BioCruces Health Research Institute, Cruces University Hospital, 48903, Barakaldo, Spain.
Gonzalo GrandesPrimary Care Research Unit of Bizkaia, BioCruces Health Research Institute, Bilbao, Spain.
Isabel AndiaRegenerative Medicine, BioCruces Health Research Institute, Cruces University Hospital, 48903, Barakaldo, Spain. iandia2010@hotmail.com.ORCID http://orcid.org/0000-0003-0607-4767
BioCruces Health research Institute · ESBasque Government · ES

Funding

Instituto de Salud Carlos III PI13/01707
6 · The paper itself

Abstract

objectiveTo investigate whether pathological changes in elbow epicondylopathy, as assessed by conventional ultrasonography and clinical outcomes, could be modified following tenotomy with platelet-rich plasma (PRP) versus tenotomy with lidocaine.

methodsThis prospective sub-study was part of a patient- and assessor-blinded, superiority-type, randomized, lidocaine-controlled trial that was performed in a tertiary hospital to assess the effectiveness of PRP versus lidocaine as tenotomy adjuvants in patients with epicondylopathy. Patients were followed after two sessions of tenotomy with either PRP or lidocaine adjuvants (4 ml) within a 2-week interval. Tendon thickness, echotexture, and neovascularization were assessed as secondary outcome measurements at baseline and at 3, 6, 12, and 20 months after treatment, and correlations with clinical outcomes were examined.

resultsTwenty months after treatment, tenotomy induced changes in tendon structure, thickness (± = 0.0006), vascularity (p < 0.0001), and echotexture (p < 0.0001). In Disabilities of the Arm, Shoulder and Hand (DASH-E) and pain (VAS-P) scores, 80.85% and 90.91% of patients showed a meaningful clinical improvement, respectively, without differences between PRP and lidocaine. There were significant differences in between-group changes in vascularity over time, p = 0.037 and p = 0.049 in the unadjusted and adjusted models, respectively. There was no relationship between pain or function and sonographic entities at the various time points.

conclusionsTwo successive needle tenotomies induced structural changes in recalcitrant epicondylopathy, with PRP displaying more vascularization and increased thickness over time compared to lidocaine. PRP compared with lidocaine did not result in improved function or decreased pain over 20 months.

Indexed as

Platelet-Rich PlasmaAnesthetics, LocalHumansLidocaineNeedlesProspective StudiesTendinopathyTenotomyTreatment OutcomeUltrasonography, InterventionalAnesthetics, LocalLidocaineElbowNeedle tenotomyPRPRCTTendinopathyUltrasoundVascularization

Identifiers

PMID30826853
OpenAlexW2919705011

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.