ArticleBMJ open2019
Uppsala Longitudinal Adolescent Depression Study (ULADS).
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Affect-Focused Psychodynamic Internet-Based Therapy for Adolescent Depression: Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Randomized controlled trial on feedback-informed internet-delivered psychodynamic therapy for adolescents with depression: A trial that failed to recruit enough participants.Internet interventions · 2026Article
- Obsessive-compulsive symptoms in adolescents with major depressive disorder: prevalence, clinical correlates, and association with childhood trauma.BMC psychiatry · 2025Article
- Low-frequency repetitive transcranial magnetic stimulation for adolescent treatment resistant depression - a feasibility study.BMC psychiatry · 2025Article
- Adult mental health outcomes of adolescent depression and co-occurring alcohol use disorder: a longitudinal cohort study.European child & adolescent psychiatry · 2025Article
- Exploring neurodevelopmental concerns: insights from a public neuropediatric learning disabilities multiprofessional outpatient facility in Brazil.Frontiers in psychology · 2025Article
- Substance Use-Related Factors and Recurrent Depression among Former Adolescent Psychiatric Inpatients.European addiction research · 2025Article
- Childhood and Adolescent Depression Symptoms and Young Adult Mental Health and Psychosocial Outcomes.JAMA network open · 2024Article
- Frontal alpha asymmetry during emotion regulation in adults with lifetime major depression.Cognitive, affective & behavioral neuroscience · 2024Article
- "It's about how you take in things with your brain" - young people's perspectives on mental health and help seeking: an interview study.BMC public health · 2024Article
- Characteristics of attentional bias in adolescents with major depressive disorders: differentiating the impact of anxious distress specifier.Frontiers in psychiatry · 2024Article
- Protocol of a prospective community-based study about the onset and course of depression in a nationally representative cohort of adults in China: the China Depression Cohort Study-I.BMC public health · 2023Article
- Early-treatment stage for adolescents with depression and their parents: An IPSE qualitative study.European child & adolescent psychiatry · 2023Article
- Epidemiology of depressive disorders among youth during Gaokao to college in China: results from Hunan Normal University mental health survey.BMC psychiatry · 2023Article
- The prevalence and risk of developing major depression among individuals with subthreshold depression in the general population.Psychological medicine · 2023Article
- Health care costs and changes in subjective health-related quality of life among Finnish adolescents referred to secondary psychiatric out-patient services: a one-year follow-up study.Scandinavian journal of child and adolescent psychiatry and psychology · 2023Article
- Serum extracellular vesicle microRNA dysregulation and childhood trauma in adolescents with major depressive disorder.Bosnian journal of basic medical sciences · 2022Article
- Familial Risk Factors in Relation to Recurrent Depression Among Former Adolescent Psychiatric Inpatients.Child psychiatry and human development · 2022Article
- Association of mental health and behavioral disorders with health care and service utilization in children before and after diagnosis.PloS one · 2022Article
- Adolescent depression, early psychiatric comorbidities, and adulthood welfare burden: a 25-year longitudinal cohort study.Social psychiatry and psychiatric epidemiology · 2021Article
Corrections and comments
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Authors and funding
15 authors.
Funding
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Abstract
purposeTo present the Uppsala Longitudinal Adolescent Depression Study, initiated in Uppsala, Sweden, in the early 1990s. The initial aim of this epidemiological investigation was to study the prevalence, characteristics and correlates of adolescent depression, and has subsequently expanded to include a broad range of social, economic and health-related long-term outcomes and cost-of-illness analyses.
participantsThe source population was first-year students (aged 16-17) in upper-secondary schools in Uppsala during 1991-1992, of which 2300 (93%) were screened for depression. Adolescents with positive screening and sex/age-matched peers were invited to a comprehensive assessment. A total of 631 adolescents (78% females) completed this assessment, and 409 subsequently completed a 15-year follow-up assessment. At both occasions, extensive information was collected on mental disorders, personality and psychosocial situation. Detailed social, economic and health-related data from 1993 onwards have recently been obtained from the Swedish national registries for 576 of the original participants and an age-matched reference population (N≥200 000). FINDINGS TO DATE: The adolescent lifetime prevalence of a major depressive episode was estimated to be 11.4%. Recurrence in young adulthood was reported by the majority, with a particularly poor prognosis for those with a persistent depressive disorder or multiple somatic symptoms. Adolescent depression was also associated with an increased risk of other adversities in adulthood, including additional mental health conditions, low educational attainment and problems related to intimate relationships. FUTURE PLANS: Longitudinal studies of adolescent depression are rare and must be responsibly managed and utilised. We therefore intend to follow the cohort continuously by means of registries. Currently, the participants are approaching mid-adulthood. At this stage, we are focusing on the overall long-term burden of adolescent depression. For this purpose, the research group has incorporated expertise in health economics. We would also welcome extended collaboration with researchers managing similar datasets.
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