Evidence map›Paper›PMID 30826689›Full record

Trial reportGait & posture2019

Correlations between patient-perceived outcome and objectively-measured biomechanical change following Total Knee Replacement.

P R Biggs, G M Whatling, C Wilson, C A Holt

Abstract readClinical Trial
In one paragraph

Trial report in Gait & posture, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Monitoring Gait Recovery After Total Knee Arthroplasty Using Wearable Sensors: Responsiveness of Gait Accelerations.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Observational
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

P R BiggsCardiff School of Engineering, College of Physical Sciences, Cardiff University, Cardiff, United Kingdom; Arthritis Research UK Biomechanics and Bioengineering Centre, Cardiff University, Cardiff, United Kingdom. Electronic address: biggs@cardiff.ac.uk.
G M WhatlingCardiff School of Engineering, College of Physical Sciences, Cardiff University, Cardiff, United Kingdom; Arthritis Research UK Biomechanics and Bioengineering Centre, Cardiff University, Cardiff, United Kingdom. Electronic address: whatlinggm@cardiff.ac.uk.
C WilsonArthritis Research UK Biomechanics and Bioengineering Centre, Cardiff University, Cardiff, United Kingdom; Department of Trauma and Orthopaedics, University Hospital of Wales, Cardiff, United Kingdom. Electronic address: wilsonsurgeon@gmail.com.
C A HoltCardiff School of Engineering, College of Physical Sciences, Cardiff University, Cardiff, United Kingdom; Arthritis Research UK Biomechanics and Bioengineering Centre, Cardiff University, Cardiff, United Kingdom. Electronic address: Holt@Cardiff.ac.uk.

Funding

Arthritis Research UK
6 · The paper itself

Abstract

backgroundTotal Knee Replacement (TKR) surgery is being utilised in a younger, more active population with greater functional expectations. Understanding whether patient-perceived measures of function reflect objective biomechanical measures is critical in understanding whether functional limitations can be adequately captured within a clinical setting. RESEARCH QUESTION: Do changes in objective gait biomechanics measures reflect patient-reported outcome measures at approximately 12 months following TKR surgery?

methodsThree-dimensional gait analysis was performed on 41 patients with OA who were scheduled for TKR surgery, 22 of which have returned for a (9-24 month) follow-up assessment. Principal Component Analysis was used to define features of variation between OA subjects and an additional 31 non-pathological control subjects. These were used to train the Cardiff Classifier, an objective classification technique, and subsequently quantify changes following TKR surgery. Patient-perceived changes were also assessed using the Oxford Knee Score (OKS), Knee Outcome Survey (KOS), and Pain Audit Collection System scores (PACS). Pearson and Spearman correlation coefficients were calculated to establish the relationship between changes in objectively-measured and perceived outcome.

resultsObjective measures of biomechanical change were strongly correlated to changes in OKS(r=-0.695, p < 0.001) and KOS(r=-.810, p < 0.001) assessed outcomes. Pain (PACS) was only related to biomechanical function post-operatively (r=-.623, p = 0.003). SIGNIFICANCE: In this biomechanics study, the relationship between changes in objective function and patient-reported measures pre to post TKR surgery is stronger than in studies which did not include biomechanics metrics. Quality of movement may hold more significance for a patient's perception of improvement than functional measures which consider only the time taken or distance travelled during functional activities.

Indexed as

Arthroplasty, Replacement, KneePatient Reported Outcome MeasuresAdultAgedBiomechanical PhenomenaCase-Control StudiesFemaleFollow-Up StudiesGaitGait AnalysisHumansKnee JointMaleMiddle AgedOsteoarthritis, KneePostoperative PeriodBiomechanicsGait analysisKnee osteoarthritisPatient reported outcome measuresPrincipal Component AnalysisTotal Knee Replacement

Identifiers

PMID30826689
PMCPMC7374408

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.