ArticleFertility and sterility2019
Risk of ischemic placental disease in fresh and frozen embryo transfer cycles.
Article in Fertility and sterility, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Does contemporary ART lead to pre-eclampsia? A cohort study and meta-analysis.Journal of assisted reproduction and genetics · 2021Pooled it
- Which is better for mothers and babies: fresh or frozen-thawed blastocyst transfer?BMC pregnancy and childbirth · 2020Pooled it
- Is live birth rate decline from frozen cycles performed during Chinese new year holiday season: A single center retrospective cohort.PloS one · 2025Article
- High concentration of estrogen resulted by COH may affect the secretion of pro-angiogenic factors in uNK cells by downregulating the expression of IL-11 in decidual stromal cells.Journal of assisted reproduction and genetics · 2024Article
- Effect of ART treatments on maternal and neonatal outcomes in singleton live births: A large-scale retrospective cohort study.Heliyon · 2024Article
- Article
- Risks of Placental Abruption and Preterm Delivery in Patients Undergoing Assisted Reproduction.JAMA network open · 2024Article
- Pregnancies through oocyte donation. A mini review of pathways involved in placental dysfunction.Frontiers in medicine · 2024Review
- Pregnancy outcomes and disease phenotype of hypertensive disorders of pregnancy in singleton pregnancies after in vitro fertilization: a retrospective analysis of 1130 cases.BMC pregnancy and childbirth · 2023Article
- Effects of Different Endometrial Preparation Regimens during IVF on Incidence of Ischemic Placental Disease for FET Cycles.Journal of clinical medicine · 2022Article
- Article
- Multifoetal gestations mediate the effect of in vitro fertilisation (IVF) on ischaemic placental disease in autologous oocyte IVF more than donor oocyte IVF.Paediatric and perinatal epidemiology · 2022Article
- Comparison of Clinical Pregnancy Outcomes after Fresh and Frozen Embryo Transfer.Computational and mathematical methods in medicine · 2022Article
- Health of 2-year-old children born after vitrified oocyte donation in comparison with peers born after fresh oocyte donation.Human reproduction open · 2021Article
- Placental histopathology in IVF pregnancies resulting from the transfer of frozen-thawed embryos compared with fresh embryos.Journal of assisted reproduction and genetics · 2020Article
- Is Embryo Cryopreservation Causing Macrosomia-and What Else?Frontiers in endocrinology · 2020Review
- Revisiting debates of premature luteinization and its effect on assisted reproductive technology outcome.Journal of assisted reproduction and genetics · 2019Review
- Risk of ischemic placental disease is increased following in vitro fertilization with oocyte donation: a retrospective cohort study.Journal of assisted reproduction and genetics · 2019Article
- Limited Effects of Ultra-low Oxygen Concentration during Extended Embryo Culture onJournal of human reproductive sciencesArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesTo evaluate the association of fresh and frozen embryo transfer with the development of ischemic placental disease (IPD), hypothesizing that differences in implantation environment affect placentation and thus pregnancy outcomes.
designWe performed a secondary analysis of a retrospective cohort study of deliveries linked to IVF cycles.
settingTertiary hospital and infertility treatment center. PATIENT(S): We included all women who underwent an autologous IVF cycle and had a live-born infant or an intrauterine fetal demise (IUFD). We excluded women less than 18 years of age. INTERVENTION(S): We compared pregnancies resulting from frozen embryo transfer (frozen) cycles with those resulting from fresh embryo transfer (fresh) cycles. MAIN OUTCOME MEASURE(S): The primary outcome was a composite outcome of IPD or IUFD due to placental insufficiency. Ischemic placental disease included pre-eclampsia, placental abruption, and small for gestational age (SGA). We calculated risk ratios (RRs) and 95% confidence intervals (CIs). RESULT(S): Compared with fresh cycles, frozen cycles had a lower risk of IPD or IUFD from placental insufficiency (RR 0.75, 95% CI 0.59-0.97). Frozen cycles also conferred a lower risk of SGA than fresh cycles (RR 0.58, 95% CI 0.41-0.81). Risks of pre-eclampsia (RR 1.3, 95% CI 0.84-1.9) and abruption (RR 1.2, 95% CI 0.56-2.4) were similar. CONCLUSION(S): There was a lower risk of IPD among frozen cycles compared with fresh cycles. This association was largely driven by lower risk of SGA among frozen cycles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.