Evidence map›Paper›PMID 30826019›Full record

ReviewPET clinics2019

PET-Based Imaging of Ischemic Heart Disease.

Kevin Chen, Edward J Miller, Mehran M Sadeghi

Abstract readReview
In one paragraph

Review in PET clinics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Coronary artery disease imaging with total-body PET.The British journal of radiology · 2026
    Review
  3. Review
  4. Myocardial Infarction with Nonobstructive Coronary Artery Disease-Definition, Etiopathogenesis, Diagnosis, and Management.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024
    Review
  5. Preclinical evaluation of [EJNMMI research · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Intensive care unit management of percutaneous mechanical circulatory supported patients: the role of imaging.European heart journal supplements : journal of the European Society of Cardiology · 2021
    Article
  11. Ischemic Heart Disease: Noninvasive Imaging Techniques and Findings.Radiographics : a review publication of the Radiological Society of North America, Inc
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kevin ChenSection of Cardiovascular Medicine, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
Edward J MillerSection of Cardiovascular Medicine, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
Mehran M SadeghiSection of Cardiovascular Medicine, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA; Veterans Affairs Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT 06516, USA. Electronic address: Mehran.Sadeghi@yale.edu.
Yale University · USVA Connecticut Healthcare System · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Novel Regulators of Calcific Aortic Valve DiseaseR01HL138567 · NHLBI · YALE UNIVERSITY · PI SADEGHI, MEHRAN M · 2017 to 2020
$2.8M
Molecular Imaging of Protease Activation in AneurysmI01BX001750 · VA · VA CONNECTICUT HEALTHCARE SYSTEM · PI SADEGHI, MEHRAN M · 2013 to 2016
–
BLRD VA I01 BX001750NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL138567
6 · The paper itself

Abstract

PET-based cardiac nuclear imaging plays a large role in the management of ischemic heart disease. Compared with conventional single-photon emission CT myocardial perfusion imaging, PET provides superior accuracy in diagnosis of coronary artery disease and, with the incorporation of myocardial blood flow and coronary flow reserve, adds value in assessing prognosis for established coronary and microvascular disease. This review describes these and other uses of PET in ischemic heart disease, including assessing myocardial viability in ischemic cardiomyopathy. Developments in novel PET flow tracers and molecular imaging tools to assess atherosclerotic plaque vulnerability, vascular calcification, and vascular remodeling also are described.

Indexed as

Computed Tomography AngiographyCoronary Artery DiseaseCoronary CirculationCost-Benefit AnalysisFractional Flow Reserve, MyocardialHumansMultimodal ImagingMyocardial IschemiaMyocardial Perfusion ImagingPositron-Emission TomographyPrognosisRadiopharmaceuticalsSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonRadiopharmaceuticalsCoronary artery diseaseCoronary flow reserveMolecular imagingMyocardial perfusion imagingMyocardial viabilityPET/CTA hybrid imaging

Identifiers

PMID30826019
PMCPMC6426655
OpenAlexW2912444489

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.