Evidence map›Paper›PMID 30825904›Full record

ArticlePregnancy hypertension2019

Risk of hypertension and abnormal biomarkers in the first year postpartum associated with hypertensive disorders of pregnancy among overweight and obese women.

Alisse Hauspurg, Malamo E Countouris, Arun Jeyabalan, Carl A Hubel, James M Roberts, Eleanor B Schwarz, Janet M Catov

Abstract read
In one paragraph

Article in Pregnancy hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 49 citations in OpenAlex.

  1. Diet Quality and Physical Activity at 3-4 Years Following a Hypertensive Pregnancy: A Blood Pressure Postpartum Cross-Sectional Sub-Study.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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  10. Examining maternal and fetal outcomes across various subtypes of hypertension during pregnancy.International journal of cardiology. Cardiovascular risk and prevention · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Alisse HauspurgDepartment of Obstetrics, Gynecology and Reproductive Sciences, Univeristy of Pittsburgh School of Medicine, United States; Magee-Womens Research Institute, University of Pittsburgh, United States. Electronic address: janickia@upmc.edu.
Malamo E CountourisUniversity of Pittsburgh Medical Center Heart and Vascular Institute, United States.
Arun JeyabalanDepartment of Obstetrics, Gynecology and Reproductive Sciences, Univeristy of Pittsburgh School of Medicine, United States; Magee-Womens Research Institute, University of Pittsburgh, United States; Clinical and Translational Science Institute, University of Pittsburgh School of Medicine, United States.
Carl A HubelDepartment of Obstetrics, Gynecology and Reproductive Sciences, Univeristy of Pittsburgh School of Medicine, United States; Magee-Womens Research Institute, University of Pittsburgh, United States.
James M RobertsDepartment of Obstetrics, Gynecology and Reproductive Sciences, Univeristy of Pittsburgh School of Medicine, United States; Magee-Womens Research Institute, University of Pittsburgh, United States; Clinical and Translational Science Institute, University of Pittsburgh School of Medicine, United States; Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, United States.
Eleanor B SchwarzUniversity of California Davis, United States.
Janet M CatovDepartment of Obstetrics, Gynecology and Reproductive Sciences, Univeristy of Pittsburgh School of Medicine, United States; Magee-Womens Research Institute, University of Pittsburgh, United States; Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, United States.
University of Pittsburgh · USUniversity of California, Davis · USUniversity of Pittsburgh Medical Center · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
TROPHOBLAST PRODUCTS IN GENESIS OF PREECLAMPSIAP01HD030367 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI HUBEL, CARL A · 1993 to 2012
$17.2M
American Heart Association-American Stroke Association 16SFRN27810001NCATS NIH HHS UL1 TR000005NICHD NIH HHS P01 HD030367
6 · The paper itself

Abstract

objectivesHypertension and obesity are common cardiometabolic risk factors in reproductive age women. The association of hypertensive disorders of pregnancy with later-life cardiovascular disease is well-established, however, it is unknown how obesity and hypertensive disorders of pregnancy converge to accelerate development of hypertension in the postpartum period. The aim of this study was to characterize rates of sustained hypertension at one year postpartum using the new American Heart Association/American College of Cardiology Guidelines among overweight and obese women with a normotensive pregnancy or hypertensive disorder of pregnancy. STUDY

design315 early pregnant women were enrolled prospectively and followed up to 12 months after delivery (mean 7.0 ± 1.8 months). At a postpartum research visit, we measured blood pressure and collected blood samples to measure cystatin C and high sensitivity C-reactive protein.

resultsA total of 254 women had a normotensive pregnancy, 39 had gestational hypertension (12.4%) and 22 had preeclampsia (7.0%). 91 women had hypertension at the postpartum study visit (28.9%). After adjustment for maternal age, BMI, lactation and time postpartum, preeclampsia was associated with an aOR 2.35 (95%CI 1.63-3.41) of development of sustained hypertension and an aOR 3.23 (95%CI 1.56-6.68) of hypertension with abnormal biomarkers compared to women with normotensive pregnancies.

conclusionsWe demonstrate a high prevalence of hypertension and abnormal biomarkers associated with hypertensive disorders of pregnancy among overweight and obese women. Our findings support the need for structured follow up and risk reduction in overweight and obese women with hypertensive disorders of pregnancy as early as the first year postpartum.

Indexed as

AdultBiomarkersC-Reactive ProteinCystatin CFemaleFollow-Up StudiesHumansHypertensionObesityOverweightPostpartum PeriodPre-EclampsiaPregnancyPrevalenceProspective StudiesRisk FactorsBiomarkersC-Reactive ProteinCystatin CCardiovascular diseaseChronic hypertensionCystatin CGestational hypertensionHsCRPPreeclampsia

Identifiers

PMID30825904
PMCPMC6400304
OpenAlexW2899244564

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.