Evidence map›Paper›PMID 30825374›Full record

SynthesisThe journals of gerontology. Series A, Biological sciences and medical sciences2019

A Multi-study Coordinated Meta-analysis of Pulmonary Function and Cognition in Aging.

Emily C Duggan, Andrea M Piccinin, Sean Clouston, Andriy V Koval, Annie Robitaille, Andrea R Zammit, Chenkai Wu, Cassandra L Brown, Lewina O Lee, Deborah Finkel and 12 more

Open access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. A Coordinated Multi-study Analysis of the Longitudinal Association Between Handgrip Strength and Cognitive Function in Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Pooled it
  3. Article
  4. Longitudinal Changes in Peak Expiratory Flow Predict Risk for Incident Dementia.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 12 institutions in 6 countries.

Emily C DugganDepartment of Psychology, University of Victoria, Victoria, BC, Canada.
Andrea M PiccininDepartment of Psychology, University of Victoria, Victoria, BC, Canada.
Sean CloustonDepartment of Family, Population and Preventive Medicine, Stony Brook University, New York.
Andriy V KovalDepartment of Psychology, University of Victoria, Victoria, BC, Canada.
Annie RobitailleDepartment of Psychology, University of Victoria, Victoria, BC, Canada.
Andrea R ZammitSaul B. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York.
Chenkai WuGlobal Health Research Center, Duke Kunshan University, China.
Cassandra L BrownDepartment of Psychology, University of Victoria, Victoria, BC, Canada.
Lewina O LeeDepartment of Psychiatry, Boston University School of Medicine, Massachusetts.
Deborah FinkelDepartment of Psychology, Indiana University Southeast, New Albany.
William H BeasleyDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City.
Jeffrey KayeDepartment of Neurology, Oregon Health & Science University, Portland.
Graciela Muniz TerreraCentre for Dementia Prevention, University of Edinburgh, UK.
Mindy KatzSaul B. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York.
Richard B LiptonSaul B. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York.
Dorly DeegDepartment of Epidemiology and Biostatistics, VU University Medical Center and Amsterdam Public Health Research Institute, the Netherlands.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois.
Marcus Praetorius BjörkDepartment of Psychology and Centre for Ageing and Health, AgeCap, University of Gothenburg, Sweden.
Boo JohanssonDepartment of Psychology and Centre for Ageing and Health, AgeCap, University of Gothenburg, Sweden.
Avron SpiroDepartment of Psychiatry, Boston University School of Medicine, Massachusetts.
Jennifer WeuveDepartment of Epidemiology, Boston University School of Public Health, Massachusetts.
Scott M HoferDepartment of Psychology, University of Victoria, Victoria, BC, Canada.
University of Victoria · CAAlbert Einstein College of Medicine · USBoston University · USOregon Health & Science University · USUniversity of Gothenburg · SEAmsterdam UMC Location Vrije Universiteit Amsterdam · NLDuke Kunshan University · CNIndiana University Southeast · USRush University Medical Center · USStony Brook University · USUniversity of Edinburgh · GBUniversity of Oklahoma Health Sciences Center · US

Funding

EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Statistical Data EnclaveP30AG012846 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI A. FREEDMAN · 1999 to 2026
$23.2M
PERSONALITY AND WELL BEING TRAJECTORIES IN ADULTHOODR01AG018436 · NIA · PURDUE UNIVERSITY WEST LAFAYETTE · PI MROCZEK, DANIEL K. · 2000 to 2020
$6.7M
GENETIC &ENVIRONMENTAL INFLUENCES--BIOBEHAVIORAL AGINGR01AG010175 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PEDERSEN, NANCY L · 1992 to 2006
$2.8M
Application of latent and integrative approaches to understand the spectrum of cognitive agingK01AG054700 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI ZAMMIT, ANDREA ROSE · 2017 to 2021
$653k
Lifespan Effects of Biologically Embedded Stress on HealthK08AG048221 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LEE, LEWINA ONYI · 2015 to 2019
$645k
NIA NIH HHS K01 AG054700NIA NIH HHS K08 AG048221NIA NIH HHS P30 AG012846NIA NIH HHS R01 AG010175NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG018436
6 · The paper itself

Abstract

backgroundSubstantial research is dedicated to understanding the aging-related dynamics among individual differences in level, change, and variation across physical and cognitive abilities. Evaluating replicability and synthesizing these findings has been limited by differences in measurements and samples, and by study design and statistical analyses confounding between-person differences with within-person changes. In this article, we conducted a coordinated analysis and summary meta-analysis of new results on the aging-related dynamics linking pulmonary function and cognitive performance.

methodsWe performed coordinated analysis of bivariate growth models in data from 20,586 participants across eight longitudinal studies to examine individual differences in baseline level, rate of change, and occasion-specific variability in pulmonary and cognitive functioning. Results were summarized using meta-analysis.

resultsWe found consistent but weak baseline and longitudinal associations in levels of pulmonary and cognitive functioning, but no associations in occasion-specific variability.

conclusionsResults provide limited evidence for a consistent link between simultaneous changes in pulmonary and cognitive function in a normal aging population. Further research is required to understand patterns of onset of decline and differences in rates of change within and across physical and cognitive functioning domains, both within-individuals and across countries and birth cohorts. Coordinated analysis provides an efficient and rigorous approach for replicating and comparing results across independent longitudinal studies.

Indexed as

AgingCognition DisordersLung DiseasesRespiratory Function TestsAgedAged, 80 and overAge FactorsComorbidityFemaleHumansLongitudinal StudiesLung Volume MeasurementsMaleMiddle AgedNeuropsychological TestsPrevalenceCognitionCognitive agingLongitudinal analysisNormative agingPulmonary

Identifiers

PMID30825374
PMCPMC6777093
OpenAlexW2918698818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.