Evidence map›Paper›PMID 30825285›Full record

ArticleCell journal2019

Histone Modification Marks Strongly Regulate CDH1 Promoter in Prostospheres as A Model of Prostate Cancer Stem Like Cells.

Fatemeh Shokraii, Maryam Moharrami, Nasrin Motamed, Maryam Shahhoseini, Mehdi Totonchi, Vahid Ezzatizadeh, Javad Firouzi, Pardis Khosravani, Marzieh Ebrahimi

Open access · greenAbstract read
In one paragraph

Article in Cell journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. A Bioinformatics and Wet-Lab-Based Pipeline IdentifiesInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Genetic and Epigenetic Alterations ofPharmaceuticals (Basel, Switzerland) · 2021
    Article
  6. Article
  7. Epigenetic Signaling and RNA Regulation in Cardiovascular Diseases.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Fatemeh Shokraii *Department of Developmental Biology, University of Science and Culture, ACECR, Tehran, Iran.
Maryam Moharrami *School of Biology, College of Science, University of Tehran, Tehran, Iran.
Nasrin MotamedSchool of Biology, College of Science, University of Tehran, Tehran, Iran. Electronic Adress:motamed2@khayam.ut.ac.ir.
Maryam ShahhoseiniDepartment of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Mehdi TotonchiDepartment of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Vahid EzzatizadehDepartment of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
Javad FirouziDepartment of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
Pardis KhosravaniDepartment of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
Marzieh EbrahimiDepartment of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. Electronic Address:mebrahimi@royaninstitute.org.
Academic Center for Education, Culture and Research · IRRoyan Institute · IRUniversity of Science and Culture · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCadherin-1 ( MATERIALS AND

methodsIn this experimental study, we isolated PCSLCs using cell surface marker and prostaspheroid formation, respectively. The cells isolated from both methods were characterized and then the levels of H3K4me2, H3K27me3, H3K9me2/3 and H3K9ac as well as DNAmet were assessed in

resultsThe CD44

conclusionOur results suggest that slight decrease of DNAmet of the CpG island in

Indexed as

Cancer Stem CellsCDH1Histone ModificationMethylationProstate Cancer

Identifiers

PMID30825285
PMCPMC6397603
OpenAlexW2981096121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.