Evidence map›Paper›PMID 30825276›Full record

ArticleCroatian medical journal2019

Malignant brain neoplasms incidence and mortality trends in Croatia from 2001 to 2014.

Goran Mrak, Valerija Korent, Ana Mišir Krpan, Andrija Bitunjac, Martina Štenger, Anton Kordić, Hrvoje Barić, Mario Šekerija

Abstract read
In one paragraph

Article in Croatian medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Goran Mrak
Valerija Korent
Ana Mišir Krpan
Andrija Bitunjac
Martina Štenger
Anton Kordić
Hrvoje Barić
Mario ŠekerijaMario Šekerija, Croatian Institute of Public Health, Rockefellerova 7, 10000 Zagreb, Croatia, mario.sekerija@hzjz.hr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo analyze the sex-specific incidence and mortality trends of brain malignancies in Croatia from 2001 to 2014.

methodsIncidence and mortality rates per 100000 population were calculated using data obtained from the Croatian National Cancer Registry and the Croatian Bureau of Statistics. Rates were age-standardized to the European Standard Population, and trends were assessed using joinpoint regression.

resultsIn the observed period there were 6634 new brain malignancy cases (52% men) and 5379 deaths due to this diagnosis (52% men). Age-standardized incidence rates ranged from 9.2-11.5 per 100000 in men and from 7-8.8 per 100000 in women. Mortality rates ranged from 7.5-8.7 per 100 000 in men and from 5-6.5 in women. Incidence trends in men, mortality in men, and mortality in women were not statistically significant, while a significant trend was observed in incidence in women (annual percent change -1.5; 95% confidence interval -2.3 to -0.6). No joinpoints were observed in any of the joinpoint analyses by sex for incidence and mortality. Age-specific incidence and mortality rates in both sexes indicate a trend shift toward older age. The proportion of morphologically verified cases ranged from 40.2%-62.4% in men and from 38.6%-56.3% in women; the proportion of death-certificate-only cases ranged from 3.3%-9.4% in men and from 3.3%-17.5% in women.

conclusionIncidence and mortality of brain malignancies in Croatia are among the highest in Europe, while reporting on brain malignancies is still poor. There is a need for improved care of patients with brain malignancies and detailed and accurate data reporting.

Indexed as

AdultAgedAge DistributionBrain NeoplasmsCroatiaDeath CertificatesEuropeFemaleHumansIncidenceMaleMiddle AgedRegistriesResearch DesignSex DistributionYoung Adult

Identifiers

PMID30825276
PMCPMC6406061

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