Evidence map›Paper›PMID 30825267›Full record

ArticleObesity (Silver Spring, Md.)2019

Increased Diet Quality is Associated with Long-Term Reduction of Abdominal and Pericardial Fat.

Rachel Hennein, Chunyu Liu, Nicola M McKeown, Udo Hoffmann, Michelle T Long, Daniel Levy, Jiantao Ma

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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  16. Nutritional genomics, inflammation and obesity.Archives of endocrinology and metabolism
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rachel HenneinPopulation Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Chunyu LiuPopulation Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Nicola M McKeownNutritional Epidemiology Program, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA.
Udo HoffmannRadiology Department, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Michelle T LongSection of Gastroenterology, Evans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Daniel LevyPopulation Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Jiantao MaPopulation Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0001-7478-7203
Boston University · USNational Institutes of Health · USTufts University · USHarvard University · US

Funding

Framingham Project/LevyZIAHL006001 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEVY, DANIEL · 2009 to 2025
$51.1M
SLEEP AND ENTRAINMENT OF SCN FUNCTIONR01HL064278 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI STROHL, KINGMAN PERKINS · 1999 to 2002
$871k
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
Intramural NIH HHS Z99 HL999999National Heart, Lung, and Blood Institute's Framingham Heart Study N01-HC-25195National Heart, Lung, and Blood Institute's Framingham Heart Study N02-HL-6-4278NHLBI NIH HHS N01 HC025195
6 · The paper itself

Abstract

objectiveThis study examined the longitudinal associations between genetic risk, change in diet quality, and change in visceral adipose tissue (ΔVAT), abdominal subcutaneous adipose tissue (ΔSAT), and pericardial adipose tissue (ΔPAT).

methodsA total of 1,677 Framingham Heart Study participants who had ectopic fat depots measured using computed tomography were analyzed. Diet quality was quantified using a Mediterranean-style diet score (MDS) and genetic risk by depot-specific genetic risk scores (GRSs).

resultsPer SD improvement in MDS, there was 50 cm

conclusionsLongitudinal improvements in diet quality are associated with less ectopic fat accumulation. This study suggests that diet quality may play a critical role in improving ectopic adiposity profiles.

Indexed as

AdiposityAdultDietDiet, MediterraneanDown-RegulationFemaleGene-Environment InteractionHumansIntra-Abdominal FatLongitudinal StudiesMaleMiddle AgedNutrition SurveysObesityOrgan SizePericardium

Identifiers

PMID30825267
PMCPMC6430652
OpenAlexW2920625688

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.