ArticleBritish journal of health psychology2019
Adherence to medication in adults with Cystic Fibrosis: An investigation using objective adherence data and the Theoretical Domains Framework.
Article in British journal of health psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Nebuliser systems for drug delivery in cystic fibrosis.The Cochrane database of systematic reviews · 2023Pooled it
- Digital technology for early identification of exacerbations in people with cystic fibrosis.The Cochrane database of systematic reviews · 2023Pooled it
- Medication adherence in youths with CKD: habits for success.Pediatric nephrology (Berlin, Germany) · 2023Trial
- Trial
- Psychosocial Aspects of Cystic Fibrosis: A Mixed-Methods Systematic Review.Healthcare (Basel, Switzerland) · 2026Review
- Association of depressive symptoms with sweat chloride variability and medication possession ratio during long-term Elexacaftor/Tezacaftor/Ivacaftor therapy in adolescents and young adults with cystic fibrosis.Frontiers in pediatrics · 2026Article
- Improving health literacy of antibiotic use in people with cystic fibrosis (CF)-comparison of the readability of patient information leaflets (PILs) from the EU, USA and UK of 23 CF-related antibiotics used in the treatment of CF respiratory infections.JAC-antimicrobial resistance · 2023Article
- Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis.The Cochrane database of systematic reviews · 2023Review
- The CFHealthHub Learning Health System: Using Real-Time Adherence Data to Support a Community of Practice to Deliver Continuous Improvement in an Archetypal Long-Term Condition.Healthcare (Basel, Switzerland) · 2022Review
- Use of mucoactive agents in cystic fibrosis: A consensus survey of Italian specialists.Health science reports · 2022Review
- Choice of methods can determine which behavioral determinates are identified for targeting in future behavior change interventions: Increasing antibiotic adherence in Pakistan.Journal of health psychology · 2022Article
- Objective Nebuliser Adherence Data as "Proof" of Adherence in the Management of Cystic Fibrosis: A Qualitative Interview Study.Patient preference and adherence · 2022Article
- "Acquiring the Skills Needed to Communicate What Is in Our Teams' Heart: Love, Compassion and Partnership": Qualitative Analysis of Intact Multidisciplinary Teams' Experience of Relationship-Centered Communication Training.Journal of patient experience · 2022Article
- Exploring the Developmental Impact of Cystic Fibrosis on Lung Transplant Candidacy: Considerations for Adulthood.Journal of clinical psychology in medical settings · 2021Article
- Patients' experiences of behaviour change interventions delivered by general practitioners during routine consultations: A nationally representative survey.Health expectations : an international journal of public participation in health care and health policy · 2021Article
- Development of an intervention to increase adherence to nebuliser treatment in adults with cystic fibrosis: CFHealthHub.Pilot and feasibility studies · 2021Article
- Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation.BMJ open · 2020Article
- Mechanisms of Action of a Web-Based Intervention With Health Professional Support to Increase Adherence to Nebulizer Treatments in Adults With Cystic Fibrosis: Qualitative Interview Study.Journal of medical Internet research · 2020Article
- What effective ways of motivation, support and technologies help people with cystic fibrosis improve and sustain adherence to treatment?BMJ open respiratory research · 2020Article
- Investigating the Temporal Relationships between Symptoms and Nebuliser Adherence in People with Cystic Fibrosis: A Series of N-of-1 Observations.Healthcare (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectivesAdherence to nebulizer treatment in adults with Cystic Fibrosis (CF) is poor, and interventions are needed. This research aimed to identify the factors affecting nebulizer adherence using the Theoretical Domains Framework (TDF) and to compare these for participants with different levels of adherence.
designData-prompted interviews using the TDF.
methodsEighteen semi-structured interviews were conducted with adults with CF during which objectively measured adherence data were discussed. Framework analysis was used to code the data into TDF domains, and inductive qualitative content analysis was used to code different beliefs and experiences. Aspects of the TDF that differed between participants with different adherence levels were explored.
resultsFactors influencing adherence to treatment included all 14 domains of the TDF, 10 of which appeared to vary by adherence level: Skills; Memory and decision-making; and Behavioural regulation; Environmental context and resources; Social influences; Beliefs about consequences; Beliefs about capability; Reinforcement; Social role and identify; Intentions; Optimism; and Emotions.
conclusionsThis study is the first to use objectively measured adherence data in a data-prompted interview using the TDF framework to systematically assess the full range of factors potentially influencing adherence. The results highlighted that interventions need to consider issues of capability, opportunity, and motivation. Interventions that challenge dysfunctional beliefs about adherence and which support the development of routines or habits and problem-solving may be particularly useful for adults with CF. Statement of contribution What is already known? Adherence to medication in adults with cystic fibrosis is poor. Previous research has identified a range of contributing factors in relation to subjective reports of adherence. There is a wide discrepancy between self-reported adherence and objectively measured adherence. What this study adds A data-prompted interview using objectively measured adherence data enabled the systematic assessment of potential factors that could be targeted in an intervention to increase adherence. There were some differences in the factors that were identified by high and low adherers. There is not one-size fits all intervention for adherence to medication in cystic fibrosis.
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Registered trials
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