Evidence map›Paper›PMID 30825012›Full record

ArticleMagma (New York, N.Y.)2019

Chemotherapy response of pancreatic cancer by diffusion-weighted imaging (DWI) and intravoxel incoherent motion DWI (IVIM-DWI) in an orthotopic mouse model.

Li Wu, Jing Li, Caixia Fu, Bernd Kühn, Xiaolin Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Li WuInstitute of Biomedical Manufacturing and Life Quality Engineering, School of Mechanical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, China. fdwl525@163.com.ORCID http://orcid.org/0000-0001-9200-9376
Jing LiInstitute of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Caixia FuMR Application Development, Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China.
Bernd KühnMR Application Predevelopment, Siemens Healthcare, Erlangen, Germany.
Xiaolin WangShanghai Institute of Medical Imaging, Shanghai, China.
Shanghai Jiao Tong University · CNFudan University · CNSiemens (China) · CNSiemens Healthineers (Germany) · DE

Funding

Shanghai Jiaotong University YG2014QN07
6 · The paper itself

Abstract

purposeTo investigate the value of using diffusion-weighted imaging (DWI) and intravoxel incoherent motion DWI (IVIM-DWI) to assess the chemotherapy response of pancreatic cancer in an orthotopic mouse model. MATERIALS AND

methodsTwenty-four BALB/C nu/nu mice in two groups (n = 12/group) with human pancreatic adenocarcinoma xenografts were dosed intravenously with saline (group 1) and gemcitabine (group 2). DWI with 3 b values (b = 50, 400 and 800 s/mm

resultsThe values of ADC and D

conclusionBoth ADC value and D

Indexed as

Diffusion Magnetic Resonance ImagingAdenocarcinomaAnimalsAntimetabolites, AntineoplasticApoptosisCell Line, TumorCell ProliferationDeoxycytidineDisease Models, AnimalGemcitabineHumansMaleMiceMice, Inbred BALB CMice, NudeMotionAntimetabolites, AntineoplasticDeoxycytidineGemcitabineDiffusion-weighted MRI (DWI)Intravoxel incoherent motion(IVIM)Pancreatic cancer

Identifiers

PMID30825012
OpenAlexW2920606165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.