ArticleInternational journal of clinical oncology2019
Diagnostic value of multimodal ultrasound imaging in differentiating benign and malignant TI-RADS category 4 nodules.
Article in International journal of clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The value of conventional ultrasound combined with superb microvascular imaging and color Doppler flow imaging in the diagnosis of thyroid malignant nodules: a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Diagnostic value of superb microvascular imaging and color doppler for thyroid nodules: A meta-analysis.Frontiers in oncology · 2023Pooled it
- Evaluating the clinical impact of integrating superb microvascular imaging and shear wave elastography into TI-RADS.Journal of ultrasound · 2025Article
- Multiparametric ultrasound techniques are superior to AI-assisted ultrasound for assessment of solid thyroid nodules: a prospective study.Endocrine · 2025Article
- Enhancing diagnostic accuracy of American College of Radiology TI-RADS 4 nodules: nomogram models based on MRI morphological features.Quantitative imaging in medicine and surgery · 2025Article
- Diagnostic value of greyscale ultrasound combined with superb microvascular imaging in thyroid nodules: a systematic review and meta-analysis.Quantitative imaging in medicine and surgery · 2025Article
- Superb microvascular imaging (SMI) and elastosonography in thyroid nodule: diagnostic value in a real-time cohort.Journal of ultrasound · 2024Article
- Combing superb microvascular imaging with shear wave elastography for risk stratification of Thyroid Imaging Reporting and Data System (TI-RADS) 4 thyroid nodules.Gland surgery · 2024Article
- The application value of deep learning-based nomograms in benign-malignant discrimination of TI-RADS category 4 thyroid nodules.Scientific reports · 2024Article
- Article
- Ultrasound microflow patterns help in distinguishing malignant from benign thyroid nodules.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- Preoperative prediction of extrathyroidal extension: radiomics signature based on multimodal ultrasound to papillary thyroid carcinoma.BMC medical imaging · 2023Article
- Diagnostic efficacy of a combination of the Chinese thyroid imaging reporting and data system and shear wave elastography in detecting category 4a and 4b thyroid nodules.Frontiers in endocrinology · 2023Article
- Artificial intelligence technology enhances the performance of shear wave elastography in thyroid nodule diagnosis.American journal of translational research · 2023Article
- Deep learning for the diagnosis of suspicious thyroid nodules based on multimodal ultrasound images.Frontiers in oncology · 2022Article
- Independent risk factors and feasibility of ultrasound diagnosis of ultrasound-guided non-cytologically diagnostic thyroid nodules.Gland surgery · 2021Article
- Evaluation of benign parotid gland tumors with superb microvascular imaging and shear wave elastography.Journal of ultrasonography · 2020Article
- Comparison of Multimodal Ultrasound Imaging with Conventional Ultrasound Risk Stratification Systems in Presurgical Risk Stratification of Thyroid Nodules.Indian journal of endocrinology and metabolismArticle
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8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDifferential diagnosis of benign and malignant thyroid imaging reporting and data system category 4 (TI-RADS-4) nodules can be difficult using conventional ultrasound (US). This study aimed to evaluate whether multimodal ultrasound imaging can improve differentiation and characterization of benign and malignant TI-RADS-4 nodules.
methodsMultimodal ultrasound imaging, including US, superb microvascular imaging (SMI), and real-time elastography (RTE), were performed on 196 TI-RADS-4 nodules (78, benign; 118, malignant) in 170 consecutive patients. The sensitivity, specificity, accuracy, false negative rate (FNR), and false positive rate (FPR) of each single method and that of multimodal US imaging were determined by comparison with surgical pathology results.
resultsThe sensitivity, specificity, accuracy, FNR, and FPR for US were 65.25%, 69.23%, 66.84%, 34.75%, 30.77%, respectively; for SMI were 77.97%, 93.59%, 84.18%, 22.03%, 6.41%, respectively; RTE, 80.51%, 84.62%, 82.14%, 19.49%, 15.38%; and for multimodal US imaging were 94.08%, 87.18%, 91.33%, 6.93%, 12.82%, respectively. The areas under the received operating characteristic curve for US, SMI, RTE, and multimodal US imaging in evaluating benign and malignant TI-RADS-4 nodules were 67.2%, 84.40%, 86.60%, and 95.50%, respectively.
conclusionsThe initial clinical results suggest that multimodal US imaging improves the diagnostic accuracy of TI-RADS-4 nodules and provides additional information for differentiating malignant and benign nodules.
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